Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOP 1.73
  2. 631650Class a: All alpha proteins [46456] (258 folds)
  3. 639436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 639437Superfamily a.26.1: 4-helical cytokines [47266] (3 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 639507Family a.26.1.2: Short-chain cytokines [47286] (11 proteins)
  6. 639530Protein Interleukin-2 (IL-2) [47301] (1 species)
  7. 639531Species Human (Homo sapiens) [TaxId:9606] [47302] (14 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1irl:
  2. Domain(s) for 1m47:
  3. Domain(s) for 1m48:
    1. 639532Domain d1m48a_: 1m48 A: [74443]
    2. 639533Domain d1m48b_: 1m48 B: [74444]
      complexed with frg
  4. Domain(s) for 1m49:
    1. 639535Domain d1m49a_: 1m49 A: [74445]
    2. 639536Domain d1m49b_: 1m49 B: [74446]
      complexed with cmm
  5. Domain(s) for 1m4a:
  6. Domain(s) for 1m4b:
  7. Domain(s) for 1m4c:
    1. 639543Domain d1m4ca_: 1m4c A: [74449]
    2. 639544Domain d1m4cb_: 1m4c B: [74450]
  8. Domain(s) for 1nbp:
  9. Domain(s) for 1pw6:
    1. 639545Domain d1pw6a_: 1pw6 A: [95200]
    2. 639546Domain d1pw6b_: 1pw6 B: [95201]
      complexed with a small molecule inhibitor
      complexed with frb, so4
  10. Domain(s) for 1py2:
    1. 639550Domain d1py2a_: 1py2 A: [95319]
    2. 639551Domain d1py2b_: 1py2 B: [95320]
    3. 639552Domain d1py2c_: 1py2 C: [95321]
    4. 639553Domain d1py2d_: 1py2 D: [95322]
      complexed with a small molecule inhibitor
      complexed with frh, zn
  11. Domain(s) for 1z92:
  12. Domain(s) for 2b5i:
  13. Domain(s) for 2erj:
    1. 639547Domain d2erjd1: 2erj D:6-133 [132294]
      Other proteins in same PDB: d2erja1, d2erja2, d2erjb1, d2erjb2, d2erjc1, d2erjc2, d2erje1, d2erje2, d2erjf1, d2erjf2, d2erjg1, d2erjg2
      automatically matched to d3inkc_
      complexed with bma, fuc, nag; mutant
    2. 639548Domain d2erjh1: 2erj H:6-133 [132301]
      Other proteins in same PDB: d2erja1, d2erja2, d2erjb1, d2erjb2, d2erjc1, d2erjc2, d2erje1, d2erje2, d2erjf1, d2erjf2, d2erjg1, d2erjg2
      automatically matched to d3inkc_
      complexed with bma, fuc, nag; mutant
  14. Domain(s) for 3ink:
    1. 639541Domain d3inkc_: 3ink C: [16881]
    2. 639542Domain d3inkd_: 3ink D: [16882]
      mutant

More info for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Interleukin-2 (IL-2)

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Interleukin-2 (IL-2):