![]() | Class a: All alpha proteins [46456] (290 folds) |
![]() | Fold a.26: 4-helical cytokines [47265] (1 superfamily) core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections |
![]() | Superfamily a.26.1: 4-helical cytokines [47266] (4 families) ![]() there are two different topoisomers of this fold with different entanglements of the two crossover connections |
![]() | Family a.26.1.2: Short-chain cytokines [47286] (14 proteins) |
![]() | Protein Interleukin-2 (IL-2) [47301] (1 species) |
![]() | Human (Homo sapiens) [TaxId:9606] [47302] (20 PDB entries) |
![]() | Domain d1irla_: 1irl A: [16883] mutant |
![]() | Domain d1m47a_: 1m47 A: [74442] complexed with so4 |
![]() | Domain d1m48a_: 1m48 A: [74443] complexed with frg |
![]() | Domain d1m48b_: 1m48 B: [74444] complexed with frg |
![]() | Domain d1m49a_: 1m49 A: [74445] complexed with cmm |
![]() | Domain d1m49b_: 1m49 B: [74446] complexed with cmm |
![]() | Domain d1m4aa_: 1m4a A: [74447] complexed with gol, mpe |
![]() | Domain d1m4ba_: 1m4b A: [74448] complexed with nmp |
![]() | Domain d1m4ca_: 1m4c A: [74449] |
![]() | Domain d1m4cb_: 1m4c B: [74450] |
![]() | Domain d1nbpa_: 1nbp A: [80392] complexed with mhc, so4 |
![]() | Domain d1pw6a_: 1pw6 A: [95200] complexed with a small molecule inhibitor complexed with frb, so4 |
![]() | Domain d1pw6b_: 1pw6 B: [95201] complexed with a small molecule inhibitor complexed with frb, so4 |
![]() | Domain d1py2a_: 1py2 A: [95319] complexed with a small molecule inhibitor complexed with frh, zn |
![]() | Domain d1py2b_: 1py2 B: [95320] complexed with a small molecule inhibitor complexed with frh, zn |
![]() | Domain d1py2c_: 1py2 C: [95321] complexed with a small molecule inhibitor complexed with frh, zn |
![]() | Domain d1py2d_: 1py2 D: [95322] complexed with a small molecule inhibitor complexed with frh, zn |
![]() | Domain d1qvna_: 1qvn A: [161678] automated match to d1irla_ complexed with fri, zn |
![]() | Domain d1qvnb_: 1qvn B: [161679] automated match to d1irla_ complexed with fri, zn |
![]() | Domain d1qvnc_: 1qvn C: [161680] automated match to d1irla_ complexed with fri, zn |
![]() | Domain d1qvnd_: 1qvn D: [161681] automated match to d1irla_ complexed with fri, zn |
![]() | Domain d1z92a_: 1z92 A: [124737] Other proteins in same PDB: d1z92b1, d1z92b2, d1z92b3 automated match to d1irl__ |
![]() | Domain d2erjd_: 2erj D: [132294] Other proteins in same PDB: d2erja1, d2erja2, d2erjb1, d2erjb2, d2erjb3, d2erjc1, d2erjc2, d2erje1, d2erje2, d2erjf1, d2erjf2, d2erjf3, d2erjg1, d2erjg2 automated match to d1irla_ complexed with nag |
![]() | Domain d2erjh_: 2erj H: [132301] Other proteins in same PDB: d2erja1, d2erja2, d2erjb1, d2erjb2, d2erjb3, d2erjc1, d2erjc2, d2erje1, d2erje2, d2erjf1, d2erjf2, d2erjf3, d2erjg1, d2erjg2 automated match to d1irla_ complexed with nag |
![]() | Domain d3inkc_: 3ink C: [16881] |
![]() | Domain d3inkd_: 3ink D: [16882] |
![]() | Domain d3qb1a_: 3qb1 A: [248836] automated match to d1irla_ mutant |
![]() | Domain d3qb1b_: 3qb1 B: [248837] automated match to d1irla_ mutant |
![]() | Domain d3qb1c_: 3qb1 C: [248838] automated match to d1irla_ mutant |
![]() | Domain d3qb1d_: 3qb1 D: [248839] automated match to d1irla_ mutant |
![]() | Domain d3qb1e_: 3qb1 E: [248840] automated match to d1irla_ mutant |
![]() | Domain d3qb1f_: 3qb1 F: [248841] automated match to d1irla_ mutant |
![]() | Domain d3qb1g_: 3qb1 G: [248842] automated match to d1irla_ mutant |
![]() | Domain d3qb1h_: 3qb1 H: [248843] automated match to d1irla_ mutant |
![]() | Domain d5utza_: 5utz A: [354734] Other proteins in same PDB: d5utzb_, d5utzc1, d5utzc2, d5utzf_, d5utzg1, d5utzg2, d5utzh_, d5utzj_, d5utzk1, d5utzk2, d5utzl1, d5utzl2 automated match to d1m48b_ complexed with gol |
![]() | Domain d5utzd_: 5utz D: [354618] Other proteins in same PDB: d5utzb_, d5utzc1, d5utzc2, d5utzf_, d5utzg1, d5utzg2, d5utzh_, d5utzj_, d5utzk1, d5utzk2, d5utzl1, d5utzl2 automated match to d1m48b_ complexed with gol |
![]() | Domain d5utze_: 5utz E: [354644] Other proteins in same PDB: d5utzb_, d5utzc1, d5utzc2, d5utzf_, d5utzg1, d5utzg2, d5utzh_, d5utzj_, d5utzk1, d5utzk2, d5utzl1, d5utzl2 automated match to d1m47a_ complexed with gol |
![]() | Domain d5utzi_: 5utz I: [354776] Other proteins in same PDB: d5utzb_, d5utzc1, d5utzc2, d5utzf_, d5utzg1, d5utzg2, d5utzh_, d5utzj_, d5utzk1, d5utzk2, d5utzl1, d5utzl2 automated match to d1m48b_ complexed with gol |
![]() | Domain d6ye3c_: 6ye3 C: [398023] Other proteins in same PDB: d6ye3b1, d6ye3b2, d6ye3e1, d6ye3e2, d6ye3h1, d6ye3h2 automated match to d1irla_ |
![]() | Domain d6ye3f_: 6ye3 F: [397931] Other proteins in same PDB: d6ye3b1, d6ye3b2, d6ye3e1, d6ye3e2, d6ye3h1, d6ye3h2 automated match to d1irla_ |
![]() | Domain d6ye3i_: 6ye3 I: [397921] Other proteins in same PDB: d6ye3b1, d6ye3b2, d6ye3e1, d6ye3e2, d6ye3h1, d6ye3h2 automated match to d1irla_ |
![]() | Domain d7dr4g_: 7dr4 G: [403251] Other proteins in same PDB: d7dr4a_, d7dr4b1, d7dr4c_, d7dr4d1, d7dr4d2, d7dr4e_, d7dr4f1, d7dr4f2, d7dr4h_, d7dr4l1, d7dr4l2 automated match to d1m47a_ |
![]() | Domain d7dr4i_: 7dr4 I: [403254] Other proteins in same PDB: d7dr4a_, d7dr4b1, d7dr4c_, d7dr4d1, d7dr4d2, d7dr4e_, d7dr4f1, d7dr4f2, d7dr4h_, d7dr4l1, d7dr4l2 automated match to d1m47a_ |
![]() | Domain d7dr4j_: 7dr4 J: [403247] Other proteins in same PDB: d7dr4a_, d7dr4b1, d7dr4c_, d7dr4d1, d7dr4d2, d7dr4e_, d7dr4f1, d7dr4f2, d7dr4h_, d7dr4l1, d7dr4l2 automated match to d1m48b_ |
![]() | Domain d7dr4k_: 7dr4 K: [403245] Other proteins in same PDB: d7dr4a_, d7dr4b1, d7dr4c_, d7dr4d1, d7dr4d2, d7dr4e_, d7dr4f1, d7dr4f2, d7dr4h_, d7dr4l1, d7dr4l2 automated match to d1m48b_ |
![]() | Domain d7m2ga_: 7m2g A: [422027] automated match to d5utza_ complexed with gol, so4; mutant |
Timeline for Protein Interleukin-2 (IL-2) from a.26.1.2: Short-chain cytokines: