Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991528Family a.26.1.2: Short-chain cytokines [47286] (14 protein domains)
  6. 1991662Protein Stem cell factor, SCF [47299] (1 species)
    forms dimer similar to the M-CSF and Flt3 ligand dimers
  7. 1991663Species Human (Homo sapiens) [TaxId:9606] [47300] (3 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1exz:
    1. 1991668Domain d1exza_: 1exz A: [16877]
      complexed with ca, sm, trs
    2. 1991669Domain d1exzb_: 1exz B: [16878]
      complexed with ca, sm, trs
    3. 1991670Domain d1exzc_: 1exz C: [16879]
      complexed with ca, sm, trs
    4. 1991671Domain d1exzd_: 1exz D: [16880]
      complexed with ca, sm, trs
  2. Domain(s) for 1scf:
    1. 1991664Domain d1scfa_: 1scf A: [16873]
      complexed with 1pe, ca
    2. 1991665Domain d1scfb_: 1scf B: [16874]
      complexed with 1pe, ca
    3. 1991666Domain d1scfc_: 1scf C: [16875]
      complexed with 1pe, ca
    4. 1991667Domain d1scfd_: 1scf D: [16876]
      complexed with 1pe, ca
  3. Domain(s) for 2e9w:

More info for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Stem cell factor, SCF

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Stem cell factor, SCF: