Class a: All alpha proteins [46456] (202 folds) |
Fold a.26: 4-helical cytokines [47265] (1 superfamily) core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections |
Superfamily a.26.1: 4-helical cytokines [47266] (3 families) there are two different topoisomers of this fold with different entanglements of the two crossover connections |
Family a.26.1.2: Short-chain cytokines [47286] (11 proteins) |
Protein Stem cell factor, SCF [47299] (1 species) forms dimer similar to the M-CSF and Flt3 ligand dimers |
Human (Homo sapiens) [TaxId:9606] [47300] (2 PDB entries) |
Domain d1exza_: 1exz A: [16877] |
Domain d1exzb_: 1exz B: [16878] |
Domain d1exzc_: 1exz C: [16879] |
Domain d1exzd_: 1exz D: [16880] complexed with ca, sm, trs |
Domain d1scfa_: 1scf A: [16873] |
Domain d1scfb_: 1scf B: [16874] |
Domain d1scfc_: 1scf C: [16875] |
Domain d1scfd_: 1scf D: [16876] complexed with 1pe, ca |
Timeline for Protein Stem cell factor, SCF from a.26.1.2: Short-chain cytokines: