Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991528Family a.26.1.2: Short-chain cytokines [47286] (14 protein domains)
  6. 1991540Protein Granulocyte-macrophage colony-stimulating factor (GM-CSF) [47289] (1 species)
  7. 1991541Species Human (Homo sapiens) [TaxId:9606] [47290] (8 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1csg:
    1. 1991546Domain d1csga1: 1csg A:5-110 [16851]
      Other proteins in same PDB: d1csga2, d1csgb2
    2. 1991547Domain d1csgb1: 1csg B:5-110 [16852]
      Other proteins in same PDB: d1csga2, d1csgb2
  2. Domain(s) for 2gmf:
    1. 1991543Domain d2gmfa1: 2gmf A:4-110 [16849]
      Other proteins in same PDB: d2gmfa2, d2gmfb2
    2. 1991544Domain d2gmfb1: 2gmf B:4-110 [16850]
      Other proteins in same PDB: d2gmfa2, d2gmfb2
  3. Domain(s) for 4nkq:
  4. Domain(s) for 4rs1:
  5. Domain(s) for 5c7x:
    1. 1991551Domain d5c7xa1: 5c7x A:9-110 [278026]
      Other proteins in same PDB: d5c7xa2, d5c7xb2, d5c7xl1, d5c7xl2, d5c7xn1, d5c7xn2
      automated match to d2gmfa_
      complexed with peg, pg6, pge
    2. 1991552Domain d5c7xb1: 5c7x B:9-110 [278027]
      Other proteins in same PDB: d5c7xa2, d5c7xb2, d5c7xl1, d5c7xl2, d5c7xn1, d5c7xn2
      automated match to d2gmfa_
      complexed with peg, pg6, pge
  6. Domain(s) for 5d70:
  7. Domain(s) for 5d71:
  8. Domain(s) for 5d72:
    1. 1991548Domain d5d72a1: 5d72 A:10-110 [278078]
      Other proteins in same PDB: d5d72a2, d5d72b2, d5d72l1, d5d72l2, d5d72n1, d5d72n2
      automated match to d1csga_
      complexed with peg
    2. 1991549Domain d5d72b1: 5d72 B:8-110 [278079]
      Other proteins in same PDB: d5d72a2, d5d72b2, d5d72l1, d5d72l2, d5d72n1, d5d72n2
      automated match to d1csga_
      complexed with peg

More info for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Granulocyte-macrophage colony-stimulating factor (GM-CSF)

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Granulocyte-macrophage colony-stimulating factor (GM-CSF):