SCOP 1.73: Species: Human (Homo sapiens) [TaxId: 9606]

Root: SCOP 1.73
Class a: All alpha proteins [46456] (258 folds)
Fold a.26: 4-helical cytokines [47265] (1 superfamily)
core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
Superfamily a.26.1: 4-helical cytokines [47266] (3 families)
there are two different topoisomers of this fold with different entanglements of the two crossover connections
Family a.26.1.2: Short-chain cytokines [47286] (11 proteins)
Protein Erythropoietin [47287] (1 species)
long chain cytokine with a short-chain cytokine topology
Species Human (Homo sapiens) [TaxId:9606] [47288] (3 PDB entries)

Domain(s) for 1buy:
- Domain d1buya_: 1buy A: [16848]
  mutant
Domain(s) for 1cn4:
- Domain d1cn4c_: 1cn4 C: [16847]
  Other proteins in same PDB: d1cn4a1, d1cn4a2, d1cn4b1, d1cn4b2
  mutant
Domain(s) for 1eer:
- Domain d1eera_: 1eer A: [16846]
  Other proteins in same PDB: d1eerb1, d1eerb2, d1eerc1, d1eerc2
  mutant

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Erythropoietin:

Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Erythropoietin first appeared (with stable ids) in SCOP 1.55
Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Erythropoietin appears in SCOP 1.71
Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Erythropoietin appears in SCOP 1.75
Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Erythropoietin appears in the current release, SCOPe 2.08