Lineage for Protein: Interleukin-6

  1. Root: SCOP 1.71
  2. 530466Class a: All alpha proteins [46456] (226 folds)
  3. 536620Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 536621Superfamily a.26.1: 4-helical cytokines [47266] (3 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 536622Family a.26.1.1: Long-chain cytokines [47267] (9 proteins)
  6. 536662Protein Interleukin-6 [47272] (2 species)

Species:

  1. 536663Human (Homo sapiens) [TaxId:9606] [47273] (4 PDB entries)
    1. Domain for 1alu:
    2. Domain for 1il6:
    3. Domain for 1p9m:
    4. Domain for 2il6:
  2. 536668Human herpesvirus 8, Kaposi's sarcoma herpes-virus [TaxId:37296] [63528] (1 PDB entry)

More info for Protein Interleukin-6 from a.26.1.1: Long-chain cytokines

Timeline for Protein Interleukin-6 from a.26.1.1: Long-chain cytokines: