SCOPe 2.08: Protein: Granulocyte-colony stimulating factor (G-CSF)

Root: SCOPe 2.08
Class a: All alpha proteins [46456] (290 folds)
Fold a.26: 4-helical cytokines [47265] (1 superfamily)
core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
Superfamily a.26.1: 4-helical cytokines [47266] (4 families)
there are two different topoisomers of this fold with different entanglements of the two crossover connections
Family a.26.1.1: Long-chain cytokines [47267] (10 proteins)
Protein Granulocyte-colony stimulating factor (G-CSF) [47268] (3 species)

Cow (Bos taurus) [TaxId:9913] [47270] (1 PDB entry)
- Domain for 1bgc:
  - Domain d1bgca_: 1bgc A: [16822]
Dog (Canis familiaris) [TaxId:9615] [47271] (2 PDB entries)
1. Domain for 1bgd:
  - Domain d1bgda_: 1bgd A: [16825]
2. Domains for 1bge:
  1. Domain d1bgea_: 1bge A: [16823]
  2. Domain d1bgeb_: 1bge B: [16824]
Human (Homo sapiens) [TaxId:9606] [47269] (4 PDB entries)
1. Domains for 1cd9:
  1. Domain d1cd9a_: 1cd9 A: [16815]
    Other proteins in same PDB: d1cd9b1, d1cd9b2, d1cd9d1, d1cd9d2
    complexed with nag
  2. Domain d1cd9c_: 1cd9 C: [16816]
    Other proteins in same PDB: d1cd9b1, d1cd9b2, d1cd9d1, d1cd9d2
    complexed with nag
2. Domain for 1gnc:
  - Domain d1gnca1: 1gnc A:2-175 [16821]
    Other proteins in same PDB: d1gnca2
3. Domains for 1pgr:
  1. Domain d1pgra_: 1pgr A: [16817]
    Other proteins in same PDB: d1pgrb1, d1pgrb2, d1pgrd1, d1pgrd2, d1pgrf1, d1pgrf2, d1pgrh1, d1pgrh2
  2. Domain d1pgrc_: 1pgr C: [16818]
    Other proteins in same PDB: d1pgrb1, d1pgrb2, d1pgrd1, d1pgrd2, d1pgrf1, d1pgrf2, d1pgrh1, d1pgrh2
  3. Domain d1pgre_: 1pgr E: [16819]
    Other proteins in same PDB: d1pgrb1, d1pgrb2, d1pgrd1, d1pgrd2, d1pgrf1, d1pgrf2, d1pgrh1, d1pgrh2
  4. Domain d1pgrg_: 1pgr G: [16820]
    Other proteins in same PDB: d1pgrb1, d1pgrb2, d1pgrd1, d1pgrd2, d1pgrf1, d1pgrf2, d1pgrh1, d1pgrh2
4. Domains for 1rhg:
  1. Domain d1rhga_: 1rhg A: [16812]
  2. Domain d1rhgb_: 1rhg B: [16813]
  3. Domain d1rhgc_: 1rhg C: [16814]

Timeline for Protein Granulocyte-colony stimulating factor (G-CSF) from a.26.1.1: Long-chain cytokines:

Protein Granulocyte-colony stimulating factor (G-CSF) from a.26.1.1: Long-chain cytokines first appeared (with stable ids) in SCOP 1.55
Protein Granulocyte-colony stimulating factor (G-CSF) from a.26.1.1: Long-chain cytokines appears in SCOPe 2.07