SCOP 1.75: Family a.25.1.1: Ferritin

Lineage for Family a.25.1.1: Ferritin

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.25: Ferritin-like [47239] (6 superfamilies)
   core: 4 helices; bundle, closed, left-handed twist; 1 crossover connection

4. Superfamily a.25.1: Ferritin-like [47240] (9 families)
   contains bimetal-ion centre in the middle of the bundle

5. Family a.25.1.1: Ferritin [47241] (9 proteins)

Proteins:

1. (Apo)ferritin [47246] (7 species)

   1. Species Bullfrog (Rana catesbeiana) [TaxId:8400] [47249] (7 PDB entries)

   2. Species Cabbage looper(Trichoplusia ni), H chain [TaxId:7111] [140437] (1 PDB entry)
      Uniprot Q8WQX3 21-211

   3. Species Cabbage looper(Trichoplusia ni), L chain [TaxId:7111] [140436] (1 PDB entry)
      Uniprot Q52SA8 1-200

   4. Species Horse (Equus caballus), L chain [TaxId:9796] [47248] (20 PDB entries)

   5. Species Human (Homo sapiens), H chain [TaxId:9606] [47247] (3 PDB entries)

   6. Species Human (Homo sapiens), mitocondial isoform [TaxId:9606] [109785] (1 PDB entry)
      Uniprot Q8N4E7

   7. Species Mouse (Mus musculus) [TaxId:10090] [63526] (2 PDB entries)

2. Bacterioferritin (cytochrome b1) [47244] (4 species)
   binds heme between two subunits; 24-mer

   1. Species Azotobacter vinelandii [TaxId:354] [140431] (3 PDB entries)
      Uniprot P22759 1-155

   2. Species Desulfovibrio desulfuricans [TaxId:876] [89025] (3 PDB entries)

   3. Species Escherichia coli [TaxId:562] [47245] (3 PDB entries)

   4. Species Rhodobacter capsulatus [TaxId:1061] [69004] (1 PDB entry)

3. Dodecameric ferritin homolog [47250] (13 species)

   1. Species Agrobacterium tumefaciens, Dps [TaxId:358] [89027] (1 PDB entry)

   2. Species Archaeon Halobacterium salinarum [TaxId:2242] [101135] (5 PDB entries)
      Uniprot Q9HMP7

   3. Species Bacillus anthracis, Dlp-1 [TaxId:1392] [74705] (1 PDB entry)

   4. Species Bacillus anthracis, Dlp-2 [TaxId:1392] [74706] (1 PDB entry)

   5. Species Bacillus brevis, Dps [TaxId:1393] [89026] (1 PDB entry)

   6. Species Escherichia coli, Dps [TaxId:562] [47251] (7 PDB entries)
      ferritin homolog that binds to and protects DNA

   7. Species Helicobacter pylori, Nap [TaxId:210] [81743] (1 PDB entry)

   8. Species Lactococcus lactis, DpsA [TaxId:1358] [140434] (1 PDB entry)
      Uniprot A2RLG8 6-173

   9. Species Lactococcus lactis, DpsB [TaxId:1358] [140433] (1 PDB entry)
      Uniprot A2RJ45 3-173

   10. Species Listeria innocua [TaxId:1642] [47252] (4 PDB entries)

   11. Species Mycobacterium smegmatis [TaxId:1772] [109784] (6 PDB entries)
       Uniprot Q8VP75

   12. Species Streptococcus suis [TaxId:1307] [101134] (4 PDB entries)

   13. Species Treponema pallidum, TpF1 [TaxId:160] [140435] (1 PDB entry)
       Uniprot P16665 26-176

4. Hypothetical protein PF1190 [140438] (1 species)
   significant sequence similarity to the half-ferritin family

   • Species Archaeon Pyrococcus furiosus [TaxId:2261] [140439] (1 PDB entry)
     Uniprot Q8U1L6 9-166

5. Hypothetical protein TM1526 [101132] (1 species)

   • Species Thermotoga maritima [TaxId:2336] [101133] (1 PDB entry)

6. Hypothetical rubrerythrin [101130] (1 species)

   • Species Archaeon Sulfolobus tokodaii [TaxId:111955] [101131] (1 PDB entry)

7. Nigerythrin, N-terminal domain [140440] (1 species)

   • Species Desulfovibrio vulgaris [TaxId:881] [140441] (3 PDB entries)
     Uniprot P30820 1-166

8. Non-hem ferritin [63524] (4 species)

   1. Species Archaeon Archaeoglobus fulgidus [TaxId:2234] [140432] (2 PDB entries)
      Uniprot O29424 3-164

   2. Species Campylobacter jejuni [TaxId:197] [69005] (1 PDB entry)

   3. Species Escherichia coli, FtnA [TaxId:562] [63525] (1 PDB entry)

   4. Species Thermotoga maritima [TaxId:2336] [109783] (1 PDB entry)
      Uniprot Q9X0L2

9. Rubrerythrin, N-terminal domain [47242] (2 species)

   1. Species Archaeon Pyrococcus furiosus [TaxId:2261] [101129] (2 PDB entries)

   2. Species Desulfovibrio vulgaris [TaxId:881] [47243] (10 PDB entries)
      Uniprot P24931

More info for Family a.25.1.1: Ferritin

Timeline for Family a.25.1.1: Ferritin:

• Family a.25.1.1: Ferritin first appeared (with stable ids) in SCOP 1.55
  
• Family a.25.1.1: Ferritin appears in SCOP 1.73
  
• Family a.25.1.1: Ferritin appears in SCOPe 2.01
  
• Family a.25.1.1: Ferritin appears in the current release, SCOPe 2.08