SCOP 1.75: Fold a.25: Ferritin-like

Lineage for Fold a.25: Ferritin-like

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.25: Ferritin-like [47239] (6 superfamilies)
   core: 4 helices; bundle, closed, left-handed twist; 1 crossover connection

Superfamilies:

1. a.25.1: Ferritin-like [47240] (9 families)
   contains bimetal-ion centre in the middle of the bundle

2. a.25.2: Cobalamin adenosyltransferase-like [89028] (2 families)
   crossover loop goes across a different side of the 4-helical bundle; no internal metal-binding site

3. a.25.3: EsxAB dimer-like [140453] (1 family)
   (hetero)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals

4. a.25.4: PE/PPE dimer-like [140459] (2 families)
   (hetero)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals inside the bundle

5. a.25.5: HP0062-like [158414] (1 family)
   (homo)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals

6. a.25.6: SO2669-like [158418] (1 family)
   (homo)dimer of alpha-hairpin subunits similar to that of the half-ferritin family; no bound metals

More info for Fold a.25: Ferritin-like

Timeline for Fold a.25: Ferritin-like:

• Fold a.25: Ferritin-like first appeared (with stable ids) in SCOP 1.55
  
• Fold a.25: Ferritin-like appears in SCOP 1.73
  
• Fold a.25: Ferritin-like appears in SCOPe 2.01
  
• Fold a.25: Ferritin-like appears in the current release, SCOPe 2.08