SCOP 1.69: Protein: Vinculin

Lineage for Protein: Vinculin

Root: SCOP 1.69
Class a: All alpha proteins [46456] (218 folds)
Fold a.24: Four-helical up-and-down bundle [47161] (23 superfamilies)
core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down
Superfamily a.24.9: alpha-catenin/vinculin [47220] (1 family)

Family a.24.9.1: alpha-catenin/vinculin [47221] (2 proteins)
possible duplication: contains several domains of this fold
The listed PDB entries contain different large fragments but not the whole proteins

Protein Vinculin [47224] (2 species)

Species:

Chicken (Gallus gallus) [TaxId:9031] [47225] (3 PDB entries)
1. Domains for 1qkr:
  1. Domain d1qkra_: 1qkr A: [16628]
  2. Domain d1qkrb_: 1qkr B: [16629]
    tail domain
2. Domains for 1st6:
  1. Domain d1st6a1: 1st6 A:1-125 [106000]
  2. Domain d1st6a2: 1st6 A:126-252 [106001]
  3. Domain d1st6a3: 1st6 A:253-371 [106002]
  4. Domain d1st6a4: 1st6 A:372-488 [106003]
  5. Domain d1st6a5: 1st6 A:489-646 [106004]
  6. Domain d1st6a6: 1st6 A:647-718 [106005]
  7. Domain d1st6a7: 1st6 A:719-855 [106006]
  8. Domain d1st6a8: 1st6 A:875-1065 [106007]
    full-length protein containing eight four-helix bundle domains
3. Domains for 1t01:
  1. Domain d1t01a1: 1t01 A:1-125 [106188]
  2. Domain d1t01a2: 1t01 A:126-252 [106189]
    complexed with Talin 1 fragment (SQ P26039 605-628), chain B
Human (Homo sapiens) [TaxId:9606] [101111] (3 PDB entries)
1. Domains for 1rkc:
  1. Domain d1rkca1: 1rkc A:1-128 [97606]
  2. Domain d1rkca2: 1rkc A:129-258 [97607]
    head domain; contains two domains of this fold; complexed with talin fragment, chain B
2. Domains for 1rke:
  1. Domain d1rkea1: 1rke A:-3-128 [97608]
  2. Domain d1rkea2: 1rke A:129-258 [97609]
    head domain; contains two domains of this fold; complexed with separate tail domain of the same or closely related protein
  3. Domain d1rkeb_: 1rke B: [97610]
    tail domain; complexed with separate head domain of the same or closely related protein
3. Domains for 1syq:
  1. Domain d1syqa1: 1syq A:1-128 [106124]
  2. Domain d1syqa2: 1syq A:129-257 [106125]
    head domain; contains two domains of this fold; complexed with talin fragment, chain B (SQ Q9Y490 607-631)

More info for Protein Vinculin from a.24.9.1: alpha-catenin/vinculin

Timeline for Protein Vinculin from a.24.9.1: alpha-catenin/vinculin:

Protein Vinculin from a.24.9.1: alpha-catenin/vinculin first appeared (with stable ids) in SCOP 1.55, called Protein Vinculin, tail domain from a.24.9.1: alpha-catenin/vinculin
Protein Vinculin from a.24.9.1: alpha-catenin/vinculin appears in SCOP 1.67
Protein Vinculin from a.24.9.1: alpha-catenin/vinculin appears in SCOP 1.71
Protein Vinculin from a.24.9.1: alpha-catenin/vinculin appears in the current release, SCOPe 2.08