Lineage for Protein: Vinculin

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1987359Fold a.24: Four-helical up-and-down bundle [47161] (28 superfamilies)
    core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down
  4. 1987801Superfamily a.24.9: alpha-catenin/vinculin-like [47220] (2 families) (S)
  5. 1987802Family a.24.9.1: alpha-catenin/vinculin [47221] (3 protein domains)
    possible duplication: contains several domains of this fold
    The listed PDB entries contain different large fragments but not the whole proteins
  6. 1987818Protein Vinculin [47224] (2 species)

Species:

  1. 1987819Chicken (Gallus gallus) [TaxId:9031] [47225] (3 PDB entries)
    Uniprot P12003
    1. Domains for 1qkr:
      1. 1987820Domain d1qkra_: 1qkr A: [16628]
        tail domain
        complexed with so4
      2. 1987821Domain d1qkrb_: 1qkr B: [16629]
        tail domain
        complexed with so4
    2. Domains for 1st6:
      1. 1987824Domain d1st6a1: 1st6 A:1-125 [106000]
        Other proteins in same PDB: d1st6a9
        full-length protein containing eight four-helix bundle domains
      2. 1987825Domain d1st6a2: 1st6 A:126-252 [106001]
        Other proteins in same PDB: d1st6a9
        full-length protein containing eight four-helix bundle domains
      3. 1987826Domain d1st6a3: 1st6 A:253-371 [106002]
        Other proteins in same PDB: d1st6a9
        full-length protein containing eight four-helix bundle domains
      4. 1987827Domain d1st6a4: 1st6 A:372-488 [106003]
        Other proteins in same PDB: d1st6a9
        full-length protein containing eight four-helix bundle domains
      5. 1987828Domain d1st6a5: 1st6 A:489-646 [106004]
        Other proteins in same PDB: d1st6a9
        full-length protein containing eight four-helix bundle domains
      6. 1987829Domain d1st6a6: 1st6 A:647-718 [106005]
        Other proteins in same PDB: d1st6a9
        full-length protein containing eight four-helix bundle domains
      7. 1987830Domain d1st6a7: 1st6 A:719-855 [106006]
        Other proteins in same PDB: d1st6a9
        full-length protein containing eight four-helix bundle domains
      8. 1987831Domain d1st6a8: 1st6 A:875-1065 [106007]
        Other proteins in same PDB: d1st6a9
        full-length protein containing eight four-helix bundle domains
    3. Domains for 1t01:
      1. 1987822Domain d1t01a1: 1t01 A:1-125 [106188]
        Other proteins in same PDB: d1t01a3
        complexed with Talin 1 fragment (Uniprot P26039 605-628), chain B
      2. 1987823Domain d1t01a2: 1t01 A:126-252 [106189]
        Other proteins in same PDB: d1t01a3
        complexed with Talin 1 fragment (Uniprot P26039 605-628), chain B
  2. 1987832Human (Homo sapiens) [TaxId:9606] [101111] (15 PDB entries)
    Uniprot P18206 1-257
    1. Domains for 1rkc:
      1. 1987852Domain d1rkca1: 1rkc A:1-128 [97606]
        head domain; contains two domains of this fold; complexed with talin fragment, chain B
      2. 1987853Domain d1rkca2: 1rkc A:129-258 [97607]
        head domain; contains two domains of this fold; complexed with talin fragment, chain B
    2. Domains for 1rke:
      1. 1987845Domain d1rkea1: 1rke A:1-128 [97608]
        Other proteins in same PDB: d1rkea3
        head domain; contains two domains of this fold; complexed with separate tail domain of the same or closely related protein
      2. 1987846Domain d1rkea2: 1rke A:129-258 [97609]
        Other proteins in same PDB: d1rkea3
        head domain; contains two domains of this fold; complexed with separate tail domain of the same or closely related protein
      3. 1987847Domain d1rkeb_: 1rke B: [97610]
        Other proteins in same PDB: d1rkea3
        tail domain; complexed with separate head domain of the same or closely related protein
    3. Domains for 1syq:
      1. 1987843Domain d1syqa1: 1syq A:1-128 [106124]
        Other proteins in same PDB: d1syqa3
        head domain; contains two domains of this fold; complexed with talin fragment, chain B (Uniprot Q9Y490 607-631)
      2. 1987844Domain d1syqa2: 1syq A:129-257 [106125]
        Other proteins in same PDB: d1syqa3
        head domain; contains two domains of this fold; complexed with talin fragment, chain B (Uniprot Q9Y490 607-631)
    4. Domain for 3myi:
    5. Domains for 3s90:
      1. 1987838Domain d3s90a1: 3s90 A:3-128 [233515]
        automated match to d1syqa1
      2. 1987839Domain d3s90a2: 3s90 A:129-250 [233516]
        automated match to d1rkea2
      3. 1987840Domain d3s90b1: 3s90 B:2-128 [233517]
        automated match to d1syqa1
      4. 1987841Domain d3s90b2: 3s90 B:129-252 [233518]
        automated match to d1rkea2
    6. Domains for 3tj5:
      1. 1987833Domain d3tj5a1: 3tj5 A:2-128 [233688]
        automated match to d1syqa1
        complexed with gol
      2. 1987834Domain d3tj5a2: 3tj5 A:129-255 [233707]
        automated match to d1rkea2
        complexed with gol
    7. Domains for 3tj6:
      1. 1987850Domain d3tj6a1: 3tj6 A:1-128 [233689]
        automated match to d1syqa1
      2. 1987851Domain d3tj6a2: 3tj6 A:129-257 [233708]
        automated match to d1rkea2
    8. Domain for 3vf0:
    9. Domains for 4dj9:
      1. 1987836Domain d4dj9a1: 4dj9 A:3-128 [251460]
        automated match to d3rf3b1
      2. 1987837Domain d4dj9a2: 4dj9 A:129-254 [251461]
        automated match to d3rf3b2
    10. Domains for 4ehp:
      1. 1987848Domain d4ehpa1: 4ehp A:2-128 [251757]
        automated match to d3s90b1
        complexed with act
      2. 1987849Domain d4ehpa2: 4ehp A:129-252 [251758]
        automated match to d3s90b2
        complexed with act
    11. Domains for 5l0c:
      1. 2278638Domain d5l0cb_: 5l0c B: [321939]
        automated match to d3vf0a_
        complexed with pio, po4
      2. 2278680Domain d5l0cd_: 5l0c D: [321981]
        automated match to d3vf0a_
        complexed with pio, po4
      3. 2278704Domain d5l0cc_: 5l0c C: [322005]
        automated match to d3vf0a_
        complexed with pio, po4
      4. 2278751Domain d5l0ca_: 5l0c A: [322052]
        automated match to d3vf0a_
        complexed with pio, po4
    12. Domains for 5l0d:
      1. 2278639Domain d5l0da_: 5l0d A: [321940]
        automated match to d3vf0a_
        complexed with pio
      2. 2278688Domain d5l0dc_: 5l0d C: [321989]
        automated match to d3vf0a_
        complexed with pio
      3. 2278714Domain d5l0dd_: 5l0d D: [322015]
        automated match to d3vf0a_
        complexed with pio
      4. 2278720Domain d5l0db_: 5l0d B: [322021]
        automated match to d3vf0a_
        complexed with pio
    13. Domains for 5l0f:
      1. 2278632Domain d5l0fa_: 5l0f A: [321933]
        automated match to d3vf0a_
        complexed with gol; mutant
      2. 2278701Domain d5l0fb_: 5l0f B: [322002]
        automated match to d3vf0a_
        complexed with gol; mutant
    14. Domain for 5l0h:
    15. Domain for 5l0i:

More info for Protein Vinculin from a.24.9.1: alpha-catenin/vinculin

Timeline for Protein Vinculin from a.24.9.1: alpha-catenin/vinculin: