Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2311272Fold a.24: Four-helical up-and-down bundle [47161] (28 superfamilies)
    core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down
  4. 2311691Superfamily a.24.7: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47212] (1 family) (S)
    automatically mapped to Pfam PF08771
  5. 2311692Family a.24.7.1: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47213] (2 proteins)
  6. 2311693Protein mTOR FKBP12–rapamycin-binding (FRB) domain [47214] (1 species)
  7. 2311694Species Human (Homo sapiens) [TaxId:9606] [47215] (11 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1aue:
    1. 2311702Domain d1auea_: 1aue A: [16615]
    2. 2311703Domain d1aueb_: 1aue B: [16616]
  2. Domain(s) for 1fap:
  3. Domain(s) for 1nsg:
  4. Domain(s) for 2fap:
  5. Domain(s) for 2gaq:
  6. Domain(s) for 3fap:
  7. Domain(s) for 4drh:
    1. 2311700Domain d4drhb1: 4drh B:2025-2112 [201732]
      Other proteins in same PDB: d4drha_, d4drhb2, d4drhd_, d4drhe2
      automated match to d4drhe_
      complexed with rap, so4
    2. 2311701Domain d4drhe1: 4drh E:2025-2112 [193177]
      Other proteins in same PDB: d4drha_, d4drhb2, d4drhd_, d4drhe2
      automated match to d1aueb_
      complexed with rap, so4
  8. Domain(s) for 4dri:
  9. Domain(s) for 4drj:
  10. Domain(s) for 4fap:
  11. Domain(s) for 4jsp:
    1. 2311706Domain d4jspa2: 4jsp A:2022-2113 [345313]
      Other proteins in same PDB: d4jspa1
      complexed with ags, mg
    2. 2311707Domain d4jspa3: 4jsp A:1385-2001 [345314]
      Other proteins in same PDB: d4jspa1
      complexed with ags, mg

More info for Species Human (Homo sapiens) [TaxId:9606] from a.24.7.1 mTOR FKBP12–rapamycin-binding (FRB) domain

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.24.7.1 mTOR FKBP12–rapamycin-binding (FRB) domain: