SCOP 1.71: Family a.29.3.1: Medium chain acyl-CoA dehydrogenase-like, C-terminal domain

Lineage for Family a.29.3.1: Medium chain acyl-CoA dehydrogenase-like, C-terminal domain

1. Root: SCOP 1.71

2. Class a: All alpha proteins [46456] (226 folds)

3. Fold a.29: Bromodomain-like [47363] (6 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.3: Acyl-CoA dehydrogenase C-terminal domain-like [47203] (2 families)
   multidomain flavoprotein; N-terminal domain is all-alpha; the middle domain is open (5,8) barrel

5. Family a.29.3.1: Medium chain acyl-CoA dehydrogenase-like, C-terminal domain [47204] (7 proteins)

Proteins:

1. 4-hydroxybutyryl-CoA dehydratase AbfD, C-terminal domain [116883] (1 species)

   • Species Clostridium aminobutyricum [TaxId:33953] [116884] (1 PDB entry)

2. Butyryl-CoA dehydrogenase, C-domain [47205] (2 species)

   1. Species Megasphaera elsdenii [TaxId:907] [47206] (1 PDB entry)

   2. Species Rat (Rattus norvegicus) [TaxId:10116] [69018] (1 PDB entry)

3. Glutaryl-CoA dehydrogenase GCDH [109794] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [109795] (2 PDB entries)

4. Isobutyryl-CoA dehydrogenase [101144] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [101145] (1 PDB entry)

5. Isovaleryl-CoA dehydrogenase, C-domain [47210] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [47211] (1 PDB entry)

6. Medium chain acyl-CoA dehydrogenase, C-domain [47207] (3 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [47209] (4 PDB entries)

   2. Species Pig (Sus scrofa) [TaxId:9823] [47208] (3 PDB entries)

   3. Species Thermus thermophilus [TaxId:274] [116882] (1 PDB entry)

7. Protein FkbI [101146] (1 species)
   involved in biosynthesis of methoxymalonyl extender unit of fk520 polyketide immunosuppressant

   • Species Streptomyces hygroscopicus [TaxId:1912] [101147] (1 PDB entry)

More info for Family a.29.3.1: Medium chain acyl-CoA dehydrogenase-like, C-terminal domain

Timeline for Family a.29.3.1: Medium chain acyl-CoA dehydrogenase-like, C-terminal domain:

• Family a.29.3.1: Medium chain acyl-CoA dehydrogenase-like, C-terminal domain first appeared (with stable ids) in SCOP 1.55, called Family a.24.6.1: Acyl-CoA dehydrogenase (flavoprotein), C-terminal domain
  
• Family a.29.3.1: Medium chain acyl-CoA dehydrogenase-like, C-terminal domain appears in SCOP 1.69
  
• Family a.29.3.1: Medium chain acyl-CoA dehydrogenase-like, C-terminal domain appears in SCOP 1.73
  
• Family a.29.3.1: Medium chain acyl-CoA dehydrogenase-like, C-terminal domain appears in the current release, SCOPe 2.08