Class a: All alpha proteins [46456] (286 folds) |
Fold a.24: Four-helical up-and-down bundle [47161] (28 superfamilies) core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down |
a.24.1: Apolipoprotein [47162] (1 family) |
a.24.2: Aspartate receptor, ligand-binding domain [47170] (2 families) automatically mapped to Pfam PF02203 |
a.24.3: Cytochromes [47175] (3 families) Heme-containing proteins |
a.24.4: Hemerythrin-like [47188] (1 family) |
a.24.5: TMV-like viral coat proteins [47195] (1 family) automatically mapped to Pfam PF00721 |
a.24.7: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47212] (1 family) automatically mapped to Pfam PF08771 |
a.24.8: Proteasome activator [47216] (1 family) |
a.24.9: alpha-catenin/vinculin-like [47220] (2 families) |
a.24.10: Histidine-containing phosphotransfer domain, HPT domain [47226] (7 families) contains additional, fifth helix at the N-terminus |
a.24.11: Bacterial GAP domain [47233] (1 family) contains extra helices in the loops at one end of the bundle |
a.24.12: Outer surface protein C (OspC) [63515] (2 families) |
a.24.13: Domain of the SRP/SRP receptor G-proteins [47364] (2 families) |
a.24.14: FAT domain of focal adhesion kinase [68993] (2 families) |
a.24.15: FAD-dependent thiol oxidase [69000] (2 families) |
a.24.16: Nucleotidyltransferase substrate binding subunit/domain [81593] (5 families) |
a.24.17: Group V grass pollen allergen [81736] (1 family) |
a.24.18: Oxygen-evolving enhancer protein 3, [101112] (1 family) automatically mapped to Pfam PF05757 |
a.24.19: Flagellar export chaperone FliS [101116] (2 families) can form closed, open and helix-swapped bundles |
a.24.20: Colicin D immunity protein [101125] (1 family) automatically mapped to Pfam PF09204 |
a.24.21: RecG, N-terminal domain [69008] (1 family) |
a.24.22: Nickel-containing superoxide dismutase, NiSOD [109770] (1 family) automatically mapped to Pfam PF09055 |
a.24.23: Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain [109775] (1 family) contains extra alpha+beta subdomain formed by the N- and C-termini. automatically mapped to Pfam PF03036 |
a.24.24: Domain from hypothetical 2610208m17rik protein [109779] (1 family) automatically mapped to Pfam PF08910 |
a.24.25: TrmE connector domain [116878] (1 family) |
a.24.26: YppE-like [140415] (1 family) flattened bundle at one end with helices 2 and coming in contact and separating helices 1 and 3 automatically mapped to Pfam PF08807 |
a.24.27: MW0975(SA0943)-like [140423] (1 family) open bundle; there is a long groove between helices 1 and 4 automatically mapped to Pfam PF10368 |
a.24.28: VPS28 C-terminal domain-like [140427] (2 families) |
a.24.29: TM1646-like [158397] (2 families) automatically mapped to Pfam PF03885 |
Timeline for Fold a.24: Four-helical up-and-down bundle: