Lineage for Family a.22.1.3: TBP-associated factors, TAFs

  1. Root: SCOP 1.67
  2. 349259Class a: All alpha proteins [46456] (202 folds)
  3. 353075Fold a.22: Histone-fold [47112] (1 superfamily)
    core: 3 helices; long middle helix is flanked at each end with shorter ones
  4. 353076Superfamily a.22.1: Histone-fold [47113] (3 families) (S)
  5. 353304Family a.22.1.3: TBP-associated factors, TAFs [47134] (11 proteins)

Proteins:

  1. 353305Histone domain of Son of sevenless protein [101107] (1 species)
  2. 353316Negative cofactor 2, NC2, alpha chain [63507] (1 species)
  3. 353319Negative cofactor 2, NC2, beta chain [63509] (1 species)
  4. 353322Nuclear transcription factor Y subunit beta (Nf-Yb3) [81724] (1 species)
    forms a heterodimer with Nf-Yc2 similar to H2A/H2B
  5. 353325Nuclear transcription factor Y subunit gamma (Nf-Yc2) [81726] (1 species)
    forms a heterodimer with Nf-Yb3 similar to H2A/H2B
  6. 353328TAF(II)-135, (TAF(II)-130, hTAF4), histone fold domain [81720] (1 species)
    lacks the third helix, forms a heterodimer with TAF(II)-20 similar to H2A-H2B
  7. 353332TAF(II)-20, (TAF(II)-15, hTAF12), histone fold domain [81722] (1 species)
    forms a heterodimer with TAF(II)-135 similar to H2A-H2B
  8. 353336TAF(II)18 [47139] (1 species)
  9. 353340TAF(II)28 [47141] (1 species)
  10. 353344TAF(II)42 [47135] (1 species)
    TAFii42 and TAFii62 form heterotetramer similar to (H3-H4)2
  11. 353347TAF(II)62 [47137] (1 species)
    TAFii42 and TAFii62 form heterotetramer similar to (H3-H4)2

More info for Family a.22.1.3: TBP-associated factors, TAFs

Timeline for Family a.22.1.3: TBP-associated factors, TAFs: