Lineage for Family a.22.1.1: Nucleosome core histones

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1987252Fold a.22: Histone-fold [47112] (1 superfamily)
    core: 3 helices; long middle helix is flanked at each end with shorter ones
  4. 1987253Superfamily a.22.1: Histone-fold [47113] (5 families) (S)
  5. 1987254Family a.22.1.1: Nucleosome core histones [47114] (6 proteins)
    form octamers composed of two copies of each of the four histones

Proteins:

  1. 1987255Histone H2A [47115] (6 species)
    1. 1987256Species African clawed frog (Xenopus laevis) [TaxId:8355] [47117] (34 PDB entries)
    2. 1987327Species Baker's yeast (Saccharomyces cerevisiae), H2A.1 [TaxId:4932] [68984] (2 PDB entries)
    3. 1987331Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47116] (6 PDB entries)
      Uniprot P02263
    4. 1987342Species Human (Homo sapiens), H2A.a [TaxId:9606] [140392] (1 PDB entry)
      Uniprot P28001 11-118
    5. 1987345Species Human (Homo sapiens), variant H2A.Z [TaxId:9606] [47118] (1 PDB entry)
    6. 1987348Species Mouse (Mus musculus), H2A.1 [TaxId:10090] [158384] (1 PDB entry)
      Uniprot P22752 14-118
  2. 1987350Histone H2B [47119] (6 species)
    1. 1987351Species African clawed frog (Xenopus laevis) [TaxId:8355] [47121] (39 PDB entries)
    2. 1987430Species Baker's yeast (Saccharomyces cerevisiae), H2B.2 [TaxId:4932] [68985] (2 PDB entries)
    3. 1987434Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47120] (6 PDB entries)
      Uniprot P02279
    4. 1987445Species Human (Homo sapiens), H2B.k [TaxId:9606] [140394] (1 PDB entry)
      Uniprot O60814 30-125
    5. 1987448Species Mouse (Mus musculus), H2Ba [TaxId:10090] [140393] (2 PDB entries)
      Uniprot Q9D2U9 34-126
    6. 1987451Species Western clawed frog (Xenopus tropicalis) [TaxId:8364] [158385] (2 PDB entries)
  3. 1987456Histone H3 [47122] (6 species)
    1. 1987457Species African clawed frog (Xenopus laevis) [TaxId:8355] [47124] (39 PDB entries)
    2. 1987537Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [68986] (1 PDB entry)
    3. 1987540Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47123] (6 PDB entries)
      Uniprot P84229
    4. 1987551Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [158386] (2 PDB entries)
    5. 1987555Species Human (Homo sapiens) [TaxId:9606] [187038] (10 PDB entries)
    6. 1987573Species Mouse (Mus musculus), H3.1 [TaxId:10090] [140395] (1 PDB entry)
      Uniprot P68433 38-135
  4. 1987576Histone H4 [47125] (7 species)
    1. 1987577Species African clawed frog (Xenopus laevis) [TaxId:8355] [47127] (57 PDB entries)
    2. 1987691Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [68987] (1 PDB entry)
    3. 1987694Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47126] (6 PDB entries)
      Uniprot P62801
    4. 1987705Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [158387] (2 PDB entries)
    5. 1987712Species Human (Homo sapiens) [TaxId:9606] [192456] (15 PDB entries)
    6. 1987732Species Kluyveromyces lactis [TaxId:284590] [189974] (1 PDB entry)
    7. 1987734Species Mouse (Mus musculus) [TaxId:10090] [47128] (1 PDB entry)
  5. 1987737macro-H2A.1, histone domain [140396] (1 species)
  6. 1987741automated matches [193445] (6 species)
    not a true protein
    1. 1987742Species African clawed frog (Xenopus laevis) [TaxId:8355] [225181] (8 PDB entries)
    2. 1987765Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [256335] (4 PDB entries)
    3. 1987786Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [225310] (17 PDB entries)
    4. 1987820Species Human (Homo sapiens) [TaxId:9606] [193446] (46 PDB entries)
    5. 1987987Species Kluyveromyces lactis [TaxId:284590] [226140] (2 PDB entries)
    6. 1987997Species Mouse (Mus musculus) [TaxId:10090] [254907] (3 PDB entries)

More info for Family a.22.1.1: Nucleosome core histones

Timeline for Family a.22.1.1: Nucleosome core histones: