Lineage for Family a.22.1.1: Nucleosome core histones

  1. Root: SCOPe 2.04
  2. 1473060Class a: All alpha proteins [46456] (285 folds)
  3. 1482597Fold a.22: Histone-fold [47112] (1 superfamily)
    core: 3 helices; long middle helix is flanked at each end with shorter ones
  4. 1482598Superfamily a.22.1: Histone-fold [47113] (5 families) (S)
  5. 1482599Family a.22.1.1: Nucleosome core histones [47114] (6 proteins)
    form octamers composed of two copies of each of the four histones

Proteins:

  1. 1482600Histone H2A [47115] (6 species)
    1. 1482601Species African clawed frog (Xenopus laevis) [TaxId:8355] [47117] (34 PDB entries)
    2. 1482672Species Baker's yeast (Saccharomyces cerevisiae), H2A.1 [TaxId:4932] [68984] (2 PDB entries)
    3. 1482676Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47116] (6 PDB entries)
      Uniprot P02263
    4. 1482687Species Human (Homo sapiens), H2A.a [TaxId:9606] [140392] (1 PDB entry)
      Uniprot P28001 11-118
    5. 1482690Species Human (Homo sapiens), variant H2A.Z [TaxId:9606] [47118] (1 PDB entry)
    6. 1482693Species Mouse (Mus musculus), H2A.1 [TaxId:10090] [158384] (1 PDB entry)
      Uniprot P22752 14-118
  2. 1482695Histone H2B [47119] (6 species)
    1. 1482696Species African clawed frog (Xenopus laevis) [TaxId:8355] [47121] (35 PDB entries)
    2. 1482767Species Baker's yeast (Saccharomyces cerevisiae), H2B.2 [TaxId:4932] [68985] (2 PDB entries)
    3. 1482771Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47120] (6 PDB entries)
      Uniprot P02279
    4. 1482782Species Human (Homo sapiens), H2B.k [TaxId:9606] [140394] (1 PDB entry)
      Uniprot O60814 30-125
    5. 1482785Species Mouse (Mus musculus), H2Ba [TaxId:10090] [140393] (2 PDB entries)
      Uniprot Q9D2U9 34-126
    6. 1482788Species Xenopus (Silurana) tropicalis [TaxId:8364] [158385] (2 PDB entries)
  3. 1482793Histone H3 [47122] (6 species)
    1. 1482794Species African clawed frog (Xenopus laevis) [TaxId:8355] [47124] (39 PDB entries)
    2. 1482874Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [68986] (1 PDB entry)
    3. 1482877Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47123] (6 PDB entries)
      Uniprot P84229
    4. 1482888Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [158386] (1 PDB entry)
    5. 1482891Species Human (Homo sapiens) [TaxId:9606] [187038] (10 PDB entries)
    6. 1482909Species Mouse (Mus musculus), H3.1 [TaxId:10090] [140395] (1 PDB entry)
      Uniprot P68433 38-135
  4. 1482912Histone H4 [47125] (7 species)
    1. 1482913Species African clawed frog (Xenopus laevis) [TaxId:8355] [47127] (38 PDB entries)
    2. 1482990Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [68987] (1 PDB entry)
    3. 1482993Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47126] (6 PDB entries)
      Uniprot P62801
    4. 1483004Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [158387] (2 PDB entries)
    5. 1483011Species Human (Homo sapiens) [TaxId:9606] [192456] (11 PDB entries)
    6. 1483025Species Kluyveromyces lactis [TaxId:284590] [189974] (1 PDB entry)
    7. 1483027Species Mouse (Mus musculus) [TaxId:10090] [47128] (1 PDB entry)
  5. 1483030macro-H2A.1, histone domain [140396] (1 species)
  6. 1483034automated matches [193445] (6 species)
    not a true protein
    1. 1483035Species African clawed frog (Xenopus laevis) [TaxId:8355] [225181] (3 PDB entries)
    2. 1483040Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [256335] (1 PDB entry)
    3. 1483047Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [225310] (2 PDB entries)
    4. 1483056Species Human (Homo sapiens) [TaxId:9606] [193446] (25 PDB entries)
    5. 1483158Species Kluyveromyces lactis [TaxId:284590] [226140] (2 PDB entries)
    6. 1483168Species Mouse (Mus musculus) [TaxId:10090] [254907] (1 PDB entry)

More info for Family a.22.1.1: Nucleosome core histones

Timeline for Family a.22.1.1: Nucleosome core histones: