Lineage for Family a.22.1.1: Nucleosome core histones

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2698054Fold a.22: Histone-fold [47112] (1 superfamily)
    core: 3 helices; long middle helix is flanked at each end with shorter ones
  4. 2698055Superfamily a.22.1: Histone-fold [47113] (5 families) (S)
  5. 2698056Family a.22.1.1: Nucleosome core histones [47114] (6 proteins)
    form octamers composed of two copies of each of the four histones

Proteins:

  1. 2698057Histone H2A [47115] (7 species)
    1. 2698058Species African clawed frog (Xenopus laevis) [TaxId:8355] [47117] (37 PDB entries)
    2. 2698137Species Baker's yeast (Saccharomyces cerevisiae), H2A.1 [TaxId:4932] [68984] (2 PDB entries)
    3. 2698141Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47116] (6 PDB entries)
      Uniprot P02263
    4. 2698152Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [419763] (3 PDB entries)
    5. 2698159Species Human (Homo sapiens), H2A.a [TaxId:9606] [140392] (5 PDB entries)
      Uniprot P28001 11-118
    6. 2698172Species Human (Homo sapiens), variant H2A.Z [TaxId:9606] [47118] (1 PDB entry)
    7. 2698175Species Mouse (Mus musculus), H2A.1 [TaxId:10090] [158384] (1 PDB entry)
      Uniprot P22752 14-118
  2. 2698177Histone H2B [47119] (6 species)
    1. 2698178Species African clawed frog (Xenopus laevis) [TaxId:8355] [47121] (42 PDB entries)
    2. 2698262Species Baker's yeast (Saccharomyces cerevisiae), H2B.2 [TaxId:4932] [68985] (2 PDB entries)
    3. 2698266Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47120] (6 PDB entries)
      Uniprot P02279
    4. 2698277Species Human (Homo sapiens), H2B.k [TaxId:9606] [140394] (4 PDB entries)
      Uniprot O60814 30-125
    5. 2698286Species Mouse (Mus musculus), H2Ba [TaxId:10090] [140393] (2 PDB entries)
      Uniprot Q9D2U9 34-126
    6. 2698289Species Western clawed frog (Xenopus tropicalis) [TaxId:8364] [158385] (3 PDB entries)
  3. 2698296Histone H3 [47122] (6 species)
    1. 2698297Species African clawed frog (Xenopus laevis) [TaxId:8355] [47124] (41 PDB entries)
    2. 2698379Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [68986] (1 PDB entry)
    3. 2698382Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47123] (6 PDB entries)
      Uniprot P84229
    4. 2698393Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [158386] (2 PDB entries)
    5. 2698397Species Human (Homo sapiens) [TaxId:9606] [187038] (23 PDB entries)
    6. 2698443Species Mouse (Mus musculus), H3.1 [TaxId:10090] [140395] (1 PDB entry)
      Uniprot P68433 38-135
  4. 2698446Histone H4 [47125] (7 species)
    1. 2698447Species African clawed frog (Xenopus laevis) [TaxId:8355] [47127] (44 PDB entries)
    2. 2698535Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [68987] (1 PDB entry)
    3. 2698538Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47126] (6 PDB entries)
      Uniprot P62801
    4. 2698549Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [158387] (2 PDB entries)
    5. 2698556Species Human (Homo sapiens) [TaxId:9606] [192456] (59 PDB entries)
    6. 2698668Species Kluyveromyces lactis [TaxId:284590] [189974] (1 PDB entry)
    7. 2698670Species Mouse (Mus musculus) [TaxId:10090] [47128] (1 PDB entry)
  5. 2698673macro-H2A.1, histone domain [140396] (1 species)
  6. 2698677automated matches [193445] (8 species)
    not a true protein
    1. 2698678Species African clawed frog (Xenopus laevis) [TaxId:8355] [225181] (11 PDB entries)
    2. 2698706Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [256335] (7 PDB entries)
    3. 2698739Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [225310] (3 PDB entries)
    4. 2698749Species Human (Homo sapiens) [TaxId:9606] [193446] (78 PDB entries)
    5. 2699039Species Kluyveromyces lactis [TaxId:284590] [226140] (3 PDB entries)
    6. 2699055Species Mouse (Mus musculus) [TaxId:10090] [254907] (4 PDB entries)
    7. 2699079Species Saccharomyces cerevisiae [TaxId:285006] [404975] (1 PDB entry)
    8. 2699096Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [391060] (3 PDB entries)

More info for Family a.22.1.1: Nucleosome core histones

Timeline for Family a.22.1.1: Nucleosome core histones: