Lineage for Family a.22.1.1: Nucleosome core histones

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2310256Fold a.22: Histone-fold [47112] (1 superfamily)
    core: 3 helices; long middle helix is flanked at each end with shorter ones
  4. 2310257Superfamily a.22.1: Histone-fold [47113] (5 families) (S)
  5. 2310258Family a.22.1.1: Nucleosome core histones [47114] (6 proteins)
    form octamers composed of two copies of each of the four histones

Proteins:

  1. 2310259Histone H2A [47115] (6 species)
    1. 2310260Species African clawed frog (Xenopus laevis) [TaxId:8355] [47117] (34 PDB entries)
    2. 2310331Species Baker's yeast (Saccharomyces cerevisiae), H2A.1 [TaxId:4932] [68984] (2 PDB entries)
    3. 2310335Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47116] (6 PDB entries)
      Uniprot P02263
    4. 2310346Species Human (Homo sapiens), H2A.a [TaxId:9606] [140392] (1 PDB entry)
      Uniprot P28001 11-118
    5. 2310349Species Human (Homo sapiens), variant H2A.Z [TaxId:9606] [47118] (1 PDB entry)
    6. 2310352Species Mouse (Mus musculus), H2A.1 [TaxId:10090] [158384] (1 PDB entry)
      Uniprot P22752 14-118
  2. 2310354Histone H2B [47119] (6 species)
    1. 2310355Species African clawed frog (Xenopus laevis) [TaxId:8355] [47121] (39 PDB entries)
    2. 2310434Species Baker's yeast (Saccharomyces cerevisiae), H2B.2 [TaxId:4932] [68985] (2 PDB entries)
    3. 2310438Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47120] (6 PDB entries)
      Uniprot P02279
    4. 2310449Species Human (Homo sapiens), H2B.k [TaxId:9606] [140394] (1 PDB entry)
      Uniprot O60814 30-125
    5. 2310452Species Mouse (Mus musculus), H2Ba [TaxId:10090] [140393] (2 PDB entries)
      Uniprot Q9D2U9 34-126
    6. 2310455Species Western clawed frog (Xenopus tropicalis) [TaxId:8364] [158385] (2 PDB entries)
  3. 2310460Histone H3 [47122] (6 species)
    1. 2310461Species African clawed frog (Xenopus laevis) [TaxId:8355] [47124] (39 PDB entries)
    2. 2310541Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [68986] (1 PDB entry)
    3. 2310544Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47123] (6 PDB entries)
      Uniprot P84229
    4. 2310555Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [158386] (2 PDB entries)
    5. 2310559Species Human (Homo sapiens) [TaxId:9606] [187038] (10 PDB entries)
    6. 2310577Species Mouse (Mus musculus), H3.1 [TaxId:10090] [140395] (1 PDB entry)
      Uniprot P68433 38-135
  4. 2310580Histone H4 [47125] (7 species)
    1. 2310581Species African clawed frog (Xenopus laevis) [TaxId:8355] [47127] (44 PDB entries)
    2. 2310664Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [68987] (1 PDB entry)
    3. 2310667Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47126] (6 PDB entries)
      Uniprot P62801
    4. 2310678Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [158387] (2 PDB entries)
    5. 2310685Species Human (Homo sapiens) [TaxId:9606] [192456] (31 PDB entries)
    6. 2310736Species Kluyveromyces lactis [TaxId:284590] [189974] (1 PDB entry)
    7. 2310738Species Mouse (Mus musculus) [TaxId:10090] [47128] (1 PDB entry)
  5. 2310741macro-H2A.1, histone domain [140396] (1 species)
  6. 2310745automated matches [193445] (6 species)
    not a true protein
    1. 2310746Species African clawed frog (Xenopus laevis) [TaxId:8355] [225181] (8 PDB entries)
    2. 2310769Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [256335] (4 PDB entries)
    3. 2310790Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [225310] (3 PDB entries)
    4. 2310800Species Human (Homo sapiens) [TaxId:9606] [193446] (49 PDB entries)
    5. 2310991Species Kluyveromyces lactis [TaxId:284590] [226140] (2 PDB entries)
    6. 2311001Species Mouse (Mus musculus) [TaxId:10090] [254907] (4 PDB entries)

More info for Family a.22.1.1: Nucleosome core histones

Timeline for Family a.22.1.1: Nucleosome core histones: