Lineage for Superfamily a.22.1: Histone-fold

  1. Root: SCOP 1.73
  2. 631650Class a: All alpha proteins [46456] (258 folds)
  3. 637441Fold a.22: Histone-fold [47112] (1 superfamily)
    core: 3 helices; long middle helix is flanked at each end with shorter ones
  4. 637442Superfamily a.22.1: Histone-fold [47113] (4 families) (S)


  1. 637443a.22.1.1: Nucleosome core histones [47114] (5 proteins)
    form octamers composed of two copies of each of the four histones
  2. 637721a.22.1.2: Archaeal histone [47129] (1 protein)
  3. 637737a.22.1.3: TBP-associated factors, TAFs [47134] (13 proteins)
  4. 637795a.22.1.4: Bacterial histone-fold protein [101318] (2 proteins)
    duplication: two repeats of histone fold are arranged as subunits in the archael histone dimer; new structure from Thermus thermophilus (1wws) comprised of dimers similar the to the H3-H4 tetramer

More info for Superfamily a.22.1: Histone-fold

Timeline for Superfamily a.22.1: Histone-fold: