SCOPe 2.08: Superfamily a.22.1: Histone-fold

Lineage for Superfamily a.22.1: Histone-fold

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.22: Histone-fold [47112] (1 superfamily)
   core: 3 helices; long middle helix is flanked at each end with shorter ones

4. Superfamily a.22.1: Histone-fold [47113] (5 families)

Families:

1. a.22.1.1: Nucleosome core histones [47114] (6 proteins)
   form octamers composed of two copies of each of the four histones

2. a.22.1.2: Archaeal histone [47129] (1 protein)

3. a.22.1.3: TBP-associated factors, TAFs [47134] (14 proteins)

4. a.22.1.4: Bacterial histone-fold protein [101318] (3 proteins)
   duplication: two repeats of histone fold are arranged as subunits in the archael histone dimer; new structure from Thermus thermophilus (1wws) comprised of dimers similar the to the H3-H4 tetramer
   automatically mapped to Pfam PF09123

5. a.22.1.0: automated matches [238448] (1 protein)
   not a true family

More info for Superfamily a.22.1: Histone-fold

Timeline for Superfamily a.22.1: Histone-fold:

• Superfamily a.22.1: Histone-fold first appeared (with stable ids) in SCOP 1.55
  
• Superfamily a.22.1: Histone-fold appears in SCOPe 2.07