Lineage for Superfamily a.22.1: Histone-fold

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1986516Fold a.22: Histone-fold [47112] (1 superfamily)
    core: 3 helices; long middle helix is flanked at each end with shorter ones
  4. 1986517Superfamily a.22.1: Histone-fold [47113] (5 families) (S)


  1. 1986518a.22.1.1: Nucleosome core histones [47114] (6 protein domains)
    form octamers composed of two copies of each of the four histones
  2. 1987113a.22.1.2: Archaeal histone [47129] (1 protein)
  3. 1987129a.22.1.3: TBP-associated factors, TAFs [47134] (14 protein domains)
  4. 1987194a.22.1.4: Bacterial histone-fold protein [101318] (3 protein domains)
    duplication: two repeats of histone fold are arranged as subunits in the archael histone dimer; new structure from Thermus thermophilus (1wws) comprised of dimers similar the to the H3-H4 tetramer
    automatically mapped to Pfam PF09123
  5. 1987211a.22.1.0: automated matches [238448] (1 protein)
    not a true family

More info for Superfamily a.22.1: Histone-fold

Timeline for Superfamily a.22.1: Histone-fold: