SCOPe 2.05: Family a.11.2.1: Second domain of FERM

Lineage for Family a.11.2.1: Second domain of FERM

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.11: Acyl-CoA binding protein-like [47026] (2 superfamilies)
   core: 3 helices; bundle, closed, left-handed twist; up-and-down

4. Superfamily a.11.2: Second domain of FERM [47031] (2 families)
   automatically mapped to Pfam PF00373

5. Family a.11.2.1: Second domain of FERM [47032] (9 proteins)

Proteins:

1. Erythroid membrane protein 4.1R [47037] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [47038] (1 PDB entry)

2. Ezrin [81714] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [81715] (1 PDB entry)

3. Focal adhesion kinase 1 [140380] (1 species)

   • Species Chicken (Gallus gallus) [TaxId:9031] [140381] (2 PDB entries)
     Uniprot Q00944 131-253

4. Merlin [68980] (2 species)
   the neurofibromatosis 2 tumor suppressor protein

   1. Species Human (Homo sapiens) [TaxId:9606] [68981] (1 PDB entry)

   2. Species Mouse (Mus musculus) [TaxId:10090] [74702] (1 PDB entry)

5. Moesin [47033] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [47034] (3 PDB entries)
     Uniprot P26038 4-297

6. Radixin [47035] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [47036] (9 PDB entries)

7. Talin [81716] (2 species)

   1. Species Chicken (Gallus gallus) [TaxId:9031] [81717] (5 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [226412] (1 PDB entry)

8. Talin-1 [116862] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [116863] (1 PDB entry)
     Uniprot P26039 209-410

9. automated matches [232256] (1 species)
   not a true protein

   • Species Mouse (Mus musculus) [TaxId:10090] [232257] (2 PDB entries)

More info for Family a.11.2.1: Second domain of FERM

Timeline for Family a.11.2.1: Second domain of FERM:

• Family a.11.2.1: Second domain of FERM first appeared (with stable ids) in SCOP 1.55
  
• Family a.11.2.1: Second domain of FERM appears in SCOPe 2.04
  
• Family a.11.2.1: Second domain of FERM appears in SCOPe 2.06
  
• Family a.11.2.1: Second domain of FERM appears in the current release, SCOPe 2.08