SCOP 1.75: Family a.6.1.3: DNA-binding N-terminal domain of transcription activators

Lineage for Family a.6.1.3: DNA-binding N-terminal domain of transcription activators

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.6: Putative DNA-binding domain [46954] (1 superfamily)
   core: 3 helices; architecture is similar to that of the "winged helix" fold but topology is different

4. Superfamily a.6.1: Putative DNA-binding domain [46955] (7 families)

5. Family a.6.1.3: DNA-binding N-terminal domain of transcription activators [46962] (4 proteins)
   includes a dimerisation, antiparallel coiled-coil subdomain

Proteins:

1. Multidrug transporter activator MtaN [68976] (1 species)

   • Species Bacillus subtilis [TaxId:1423] [68977] (2 PDB entries)
     Uniprot P71039 1-109

2. Transcription activator BmrR [46963] (1 species)
   followed by long alpha-helical linker

   • Species Bacillus subtilis [TaxId:1423] [46964] (7 PDB entries)
     Uniprot P39075

3. Transcriptional regulator CueR [101073] (1 species)
   copper efflux regulator

   • Species Escherichia coli [TaxId:562] [101074] (3 PDB entries)

4. Transcriptional regulator ZntR [101075] (1 species)
   Zn(II)-responsive regulator of ZntA

   • Species Escherichia coli [TaxId:562] [101076] (3 PDB entries)

More info for Family a.6.1.3: DNA-binding N-terminal domain of transcription activators

Timeline for Family a.6.1.3: DNA-binding N-terminal domain of transcription activators:

• Family a.6.1.3: DNA-binding N-terminal domain of transcription activators first appeared (with stable ids) in SCOP 1.55, called Family a.6.1.3: DNA-binding domain of transcription activator BmrR
  
• Family a.6.1.3: DNA-binding N-terminal domain of transcription activators appears in SCOP 1.73
  
• Family a.6.1.3: DNA-binding N-terminal domain of transcription activators appears in SCOPe 2.01
  
• Family a.6.1.3: DNA-binding N-terminal domain of transcription activators appears in the current release, SCOPe 2.08