SCOPe 2.08: Family a.4.6.1: PhoB-like

Lineage for Family a.4.6.1: PhoB-like

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.6: C-terminal effector domain of the bipartite response regulators [46894] (4 families)
   binds to DNA and RNA polymerase; the N-terminal, receiver domain belongs to the CheY family

5. Family a.4.6.1: PhoB-like [46895] (6 proteins)
   contains 4-stranded meander beta-sheet in the N-terminal extension

Proteins:

1. OmpR [46896] (1 species)

   • Species Escherichia coli [TaxId:562] [46897] (3 PDB entries)

2. PhoB [46898] (2 species)

   1. Species Escherichia coli [TaxId:562] [46899] (4 PDB entries)

   2. Species Thermotoga maritima [TaxId:2336] [68972] (1 PDB entry)

3. Probable regulatory protein EmbR [140313] (1 species)
   N-terminal domain, unlike the other members

   • Species Mycobacterium tuberculosis [TaxId:1773] [140314] (2 PDB entries)
     Uniprot P66799 10-104

4. Response regulator DrrB [88988] (1 species)

   • Species Thermotoga maritima [TaxId:2336] [88989] (1 PDB entry)

5. Transcriptional regulatory protein PrrA [140315] (1 species)

   • Species Mycobacterium tuberculosis [TaxId:1773] [140316] (2 PDB entries)
     Uniprot P0A5Z6 128-233

6. automated matches [397206] (1 species)
   not a true protein

   • Species Escherichia coli [TaxId:562] [397207] (1 PDB entry)

More info for Family a.4.6.1: PhoB-like

Timeline for Family a.4.6.1: PhoB-like:

• Family a.4.6.1: PhoB-like first appeared (with stable ids) in SCOP 1.55
  
• Family a.4.6.1: PhoB-like appears in SCOPe 2.07