Lineage for Family a.4.6.1: PhoB-like

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1981147Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. 1984099Superfamily a.4.6: C-terminal effector domain of the bipartite response regulators [46894] (4 families) (S)
    binds to DNA and RNA polymerase; the N-terminal, receiver domain belongs to the CheY family
  5. 1984100Family a.4.6.1: PhoB-like [46895] (5 protein domains)
    contains 4-stranded meander beta-sheet in the N-terminal extension

Protein Domains:

  1. 1984101OmpR [46896] (1 species)
  2. 1984106PhoB [46898] (2 species)
    1. 1984107Species Escherichia coli [TaxId:562] [46899] (4 PDB entries)
    2. 1984115Species Thermotoga maritima [TaxId:2336] [68972] (1 PDB entry)
  3. 1984117Probable regulatory protein EmbR [140313] (1 species)
    N-terminal domain, unlike the other members
  4. 1984122Response regulator DrrB [88988] (1 species)
  5. 1984125Transcriptional regulatory protein PrrA [140315] (1 species)

More info for Family a.4.6.1: PhoB-like

Timeline for Family a.4.6.1: PhoB-like: