SCOP 1.75: Family a.4.5.5: ArsR-like transcriptional regulators

Lineage for Family a.4.5.5: ArsR-like transcriptional regulators

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.5: "Winged helix" DNA-binding domain [46785] (84 families)
   contains a small beta-sheet (wing)

5. Family a.4.5.5: ArsR-like transcriptional regulators [46801] (4 proteins)
   The N- and C-terminal helical extensions to the common fold form the dimer interface

Proteins:

1. Cadmium efflux system accessory protein CadC [140239] (1 species)

   • Species Staphylococcus aureus [TaxId:1280] [140240] (1 PDB entry)
     Uniprot P20047 12-119

2. Metal-sensing transcriptional repressor CzrA [109664] (1 species)

   • Species Staphylococcus aureus [TaxId:1280] [109665] (2 PDB entries)
     Uniprot O85142

3. Putative arsenical resistance operon repressor AF0168 [116786] (1 species)
   lacks the extra C-terminal helix

   • Species Archaeoglobus fulgidus [TaxId:2234] [116787] (1 PDB entry)
     Uniprot O30069

4. SmtB repressor [46802] (1 species)

   • Species Cyanobacteria (Synechococcus), pcc7942 [TaxId:1129] [46803] (4 PDB entries)
     Uniprot P30340

More info for Family a.4.5.5: ArsR-like transcriptional regulators

Timeline for Family a.4.5.5: ArsR-like transcriptional regulators:

• Family a.4.5.5: ArsR-like transcriptional regulators first appeared (with stable ids) in SCOP 1.55
  
• Family a.4.5.5: ArsR-like transcriptional regulators appears in SCOP 1.73
  
• Family a.4.5.5: ArsR-like transcriptional regulators appears in SCOPe 2.01
  
• Family a.4.5.5: ArsR-like transcriptional regulators appears in the current release, SCOPe 2.08