SCOPe 2.06: Family a.4.1.7: Centromere-binding

Lineage for Family a.4.1.7: Centromere-binding

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.1: Homeodomain-like [46689] (20 families)
   consists only of helices

5. Family a.4.1.7: Centromere-binding [46756] (2 proteins)
   duplication: tandem repeat of two similar domains

Proteins:

1. Ars-binding protein 1, ABP1 [74670] (1 species)

   • Species Fission yeast (Schizosaccharomyces pombe) [TaxId:4896] [74671] (1 PDB entry)

2. DNA-binding domain of centromere binding protein B (CENP-B) [46757] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [46758] (2 PDB entries)

More info for Family a.4.1.7: Centromere-binding

Timeline for Family a.4.1.7: Centromere-binding:

• Family a.4.1.7: Centromere-binding first appeared (with stable ids) in SCOP 1.55, called Family a.4.1.7: DNA-binding domain of centromere binding protein B (CENP-B)
  
• Family a.4.1.7: Centromere-binding appears in SCOPe 2.05
  
• Family a.4.1.7: Centromere-binding appears in SCOPe 2.07
  
• Family a.4.1.7: Centromere-binding appears in the current release, SCOPe 2.08