Lineage for Family a.4.1.1: Homeodomain

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1981563Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. 1981564Superfamily a.4.1: Homeodomain-like [46689] (20 families) (S)
    consists only of helices
  5. 1981565Family a.4.1.1: Homeodomain [46690] (41 proteins)
    Pfam PF00046

Proteins:

  1. 1981566Antennapedia Homeodomain [46716] (1 species)
  2. 1981574DNA-binding protein SATB2 [116776] (1 species)
  3. 1981577Engrailed Homeodomain [46691] (1 species)
  4. 1981603Even-skipped homeodomain [63465] (1 species)
  5. 1981607Extradenticle (exd) homeodomain [46720] (1 species)
  6. 1981610Fushi Tarazu protein [46722] (1 species)
  7. 1981613Hepatocyte nuclear factor 1a (LFB1/HNF1) [46697] (2 species)
    atypical Homeodomain with a large insertion into HTH motif
    1. 1981614Species Human (Homo sapiens) [TaxId:9606] [81680] (1 PDB entry)
    2. 1981617Species Rat (Rattus rattus) [TaxId:10117] [46698] (2 PDB entries)
  8. 1981620Hepatocyte nuclear factor 6 [116780] (1 species)
  9. 1981623Homeo-prospero domain of Prospero protein [81681] (1 species)
    single domain composed of a homeodomain-homology N-terminal region (1245-1295) and the prospero-specific C-terminal region (1296-1396) that forms a 4-helical bundle
  10. 1981627Homeobox protein hox-a9 [100994] (1 species)
  11. 1981630Homeobox protein hox-b1 [46709] (1 species)
  12. 1981633Homeobox protein hox-b13 [140161] (1 species)
  13. 1981636Homeobox protein pknox1 [140153] (1 species)
  14. 1981639Homeobox protein prh [140149] (1 species)
  15. 1981642Homeobox-containing protein 1, HMBOX1 (Flj21616) [140159] (1 species)
  16. 1981645Homeobox-leucine zipper protein Homez [116778] (1 species)
  17. 1981648Homeodomain-only protein, Hop [109647] (1 species)
  18. 1981651Homeotic bicoid protein [140155] (1 species)
  19. 1981654Hypothetical protein 4930532d21rik [140157] (1 species)
  20. 1981657Insulin gene enhancer protein isl-1 [46714] (1 species)
  21. 1981660LAG1 longevity assurance homolog 5, LASS5 [140141] (1 species)
  22. 1981663Lag1 longevity assurance homolog 6, LASS6 [140147] (1 species)
  23. 1981666mat alpha2 Homeodomain [46695] (1 species)
  24. 1981679Mating type protein A1 Homeodomain [46693] (1 species)
  25. 1981687Msx-1 homeodomain [63463] (1 species)
  26. 1981690Oct-1 POU Homeodomain [46699] (1 species)
  27. 1981701Oct-2 POU Homeodomain [46705] (1 species)
  28. 1981704Oct-3 POU Homeodomain [46707] (1 species)
  29. 1981707Paired box protein pax6 [140143] (1 species)
  30. 1981710Paired protein [46726] (1 species)
  31. 1981715pbx1 [46711] (2 species)
    1. 1981716Species Human (Homo sapiens) [TaxId:9606] [46712] (2 PDB entries)
    2. 1981719Species Mouse (Mus musculus) [TaxId:10090] [46713] (2 PDB entries)
  32. 1981722Pit-1 POU homeodomain [46701] (1 species)
  33. 1981726Pituitary homeobox 2 [140151] (1 species)
  34. 1981729Thyroid transcription factor 1 homeodomain [46703] (1 species)
  35. 1981732Transcriptional adaptor 2-like, TADA2L, isoform b [140145] (1 species)
  36. 1981735Ultrabithorax (ubx) homeodomain [46718] (1 species)
  37. 1981738VND/NK-2 protein [46724] (1 species)
  38. 1981744ZF-HD homeobox protein At4g24660 [116774] (1 species)
  39. 1981747ZF-HD homeobox protein At5g65410 [116772] (1 species)
  40. 1981750Zinc fingers and homeoboxes protein 1, ZHX1 [158242] (1 species)
  41. 1981756automated matches [190360] (3 species)
    not a true protein
    1. 1981757Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [187191] (6 PDB entries)
    2. 1981769Species Human (Homo sapiens) [TaxId:9606] [188758] (10 PDB entries)
    3. 1981783Species Mouse (Mus musculus) [TaxId:10090] [255210] (1 PDB entry)

More info for Family a.4.1.1: Homeodomain

Timeline for Family a.4.1.1: Homeodomain: