Lineage for Family a.4.1.1: Homeodomain

  1. Root: SCOP 1.63
  2. 208553Class a: All alpha proteins [46456] (171 folds)
  3. 210246Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (11 superfamilies)
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. 210247Superfamily a.4.1: Homeodomain-like [46689] (11 families) (S)
    consists only of helices
  5. 210248Family a.4.1.1: Homeodomain [46690] (21 proteins)

Proteins:

  1. 210249Antennapedia Homeodomain [46716] (1 species)
  2. 210257Engrailed Homeodomain [46691] (1 species)
  3. 210268Even-skipped homeodomain [63465] (1 species)
  4. 210272Extradenticle (exd) homeodomain [46720] (1 species)
  5. 210275Fushi Tarazu protein [46722] (1 species)
  6. 210278Hepatocyte nuclear factor 1a (LFB1/HNF1) [46697] (2 species)
    atypical Homeodomain with a large insertion into HTH motif
    1. 210279Species Human (Homo sapiens) [TaxId:9606] [81680] (1 PDB entry)
    2. 210282Species Rat (Rattus rattus) [TaxId:10117] [46698] (2 PDB entries)
  7. 210285Homeo-prospero domain of Prospero protein [81681] (1 species)
    single domain composed of a homeodomain-homology N-terminal region (1245-1295) and the prospero-specific C-terminal region (1296-1396) that forms a 4-helical bundle
  8. 210288Homeobox protein hox-b1 [46709] (1 species)
  9. 210291Insulin gene enhancer protein isl-1 [46714] (1 species)
  10. 210294mat alpha2 Homeodomain [46695] (1 species)
  11. 210307Mating type protein A1 Homeodomain [46693] (1 species)
  12. 210315Msx-1 homeodomain [63463] (1 species)
  13. 210318Oct-1 POU Homeodomain [46699] (1 species)
  14. 210328Oct-2 POU Homeodomain [46705] (1 species)
  15. 210331Oct-3 POU Homeodomain [46707] (1 species)
  16. 210334Paired protein [46726] (1 species)
  17. 210339pbx1 [46711] (2 species)
    1. 210340Species Human (Homo sapiens) [TaxId:9606] [46712] (1 PDB entry)
    2. 210342Species Mouse (Mus musculus) [TaxId:10090] [46713] (2 PDB entries)
  18. 210345Pit-1 POU homeodomain [46701] (1 species)
  19. 210349Thyroid transcription factor 1 homeodomain [46703] (1 species)
  20. 210352Ultrabithorax (ubx) homeodomain [46718] (1 species)
  21. 210355VND/NK-2 protein [46724] (1 species)

More info for Family a.4.1.1: Homeodomain

Timeline for Family a.4.1.1: Homeodomain: