Lineage for Fold a.2: Long alpha-hairpin

  1. Root: SCOPe 2.02
  2. 1074916Class a: All alpha proteins [46456] (284 folds)
  3. 1077399Fold a.2: Long alpha-hairpin [46556] (20 superfamilies)
    2 helices; antiparallel hairpin, left-handed twist

Superfamilies:

  1. 1077400a.2.1: GreA transcript cleavage protein, N-terminal domain [46557] (1 family) (S)
  2. 1077416a.2.2: Ribosomal protein L29 (L29p) [46561] (1 family) (S)
  3. 1077513a.2.3: Chaperone J-domain [46565] (2 families) (S)
  4. 1077552a.2.5: Prefoldin [46579] (1 family) (S)
  5. 1077561a.2.6: HR1 repeat [46585] (1 family) (S)
  6. 1077568a.2.7: tRNA-binding arm [46589] (4 families) (S)
    formerly a class II aminoacyl-tRNA synthetase N-domain
  7. 1077598a.2.8: Eukaryotic DNA topoisomerase I, dispensable insert domain [46596] (1 family) (S)
  8. 1077611a.2.9: C-terminal UvrC-binding domain of UvrB [46600] (1 family) (S)
  9. 1077619a.2.10: Epsilon subunit of F1F0-ATP synthase C-terminal domain [46604] (1 family) (S)
  10. 1077632a.2.11: Fe,Mn superoxide dismutase (SOD), N-terminal domain [46609] (1 family) (S)
  11. 1077878a.2.12: Sporulation inhibitor Sda [100985] (1 family) (S)
  12. 1077890a.2.13: Transcriptional repressor TraM [109631] (1 family) (S)
    similar structure to L29p (46561); contains extra short helix; forms homodimer: an open bundle
  13. 1077906a.2.14: DnaK suppressor protein DksA, alpha-hairpin domain [109635] (1 family) (S)
  14. 1077920a.2.15: ISY1 domain-like [140102] (1 family) (S)
  15. 1077925a.2.16: Calcyclin-binding protein-like [140106] (1 family) (S)
  16. 1077934a.2.17: Endosomal sorting complex assembly domain [140111] (3 families) (S)
    forms 'fan'-like heterooligomers, in which the domains of different subunit make similar interactions at the tip of the hairpin
  17. 1077962a.2.18: SPy1572-like [140121] (1 family) (S)
    forms homodimer: an open bundle, different from the TRAM dimer
  18. 1077967a.2.19: Rabenosyn-5 Rab-binding domain-like [140125] (1 family) (S)
  19. 1077977a.2.20: MxiH-like [140129] (2 families) (S)
    Type III secretion system needle
  20. 1077992a.2.21: YnzC-like [158221] (1 family) (S)

More info for Fold a.2: Long alpha-hairpin

Timeline for Fold a.2: Long alpha-hairpin: