SCOP 1.71: Fold a.2: Long alpha-hairpin

Lineage for Fold a.2: Long alpha-hairpin

1. Root: SCOP 1.71

2. Class a: All alpha proteins [46456] (226 folds)

3. Fold a.2: Long alpha-hairpin [46556] (13 superfamilies)
   2 helices; antiparallel hairpin, left-handed twist

Superfamilies:

1. a.2.1: GreA transcript cleavage protein, N-terminal domain [46557] (1 family)

2. a.2.2: Ribosomal protein L29 (L29p) [46561] (1 family)

3. a.2.3: Chaperone J-domain [46565] (1 family)

4. a.2.5: Prefoldin [46579] (1 family)

5. a.2.6: HR1 repeat [46585] (1 family)

6. a.2.7: tRNA-binding arm [46589] (4 families)
   formerly a class II aminoacyl-tRNA synthetase N-domain

7. a.2.8: Eukaryotic DNA topoisomerase I, dispensable insert domain [46596] (1 family)

8. a.2.9: C-terminal UvrC-binding domain of UvrB [46600] (1 family)

9. a.2.10: Epsilon subunit of F1F0-ATP synthase C-terminal domain [46604] (1 family)

10. a.2.11: Fe,Mn superoxide dismutase (SOD), N-terminal domain [46609] (1 family)

11. a.2.12: Sporulation inhibitor Sda [100985] (1 family)

12. a.2.13: Transcriptional repressor TraM [109631] (1 family)
    similar structure to L29p (scop_sf 46561); contains extra short helix; forms homodimer: an open bundle

13. a.2.14: DnaK suppressor protein DksA, alpha-hairpin domain [109635] (1 family)

More info for Fold a.2: Long alpha-hairpin

Timeline for Fold a.2: Long alpha-hairpin:

• Fold a.2: Long alpha-hairpin first appeared (with stable ids) in SCOP 1.55
  
• Fold a.2: Long alpha-hairpin appears in SCOP 1.69
  
• Fold a.2: Long alpha-hairpin appears in SCOP 1.73
  
• Fold a.2: Long alpha-hairpin appears in the current release, SCOPe 2.08