SCOP 1.73: Domain d1b8mb_: 1b8m B:

Lineage for d1b8mb_ (1b8m B:)

1. Root: SCOP 1.73

2. Class g: Small proteins [56992] (85 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (7 families)

5. Family g.17.1.3: Neurotrophin [57520] (4 proteins)

6. Protein Neurotrophin 4, NT4 [57523] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57524] (3 PDB entries)

8. Domain d1b8mb_: 1b8m B: [44798]
   Other proteins in same PDB: d1b8ma_
   heterodimer with BDNF

Details for d1b8mb_

PDB Entry: 1b8m, 2.75 Å

PDB Description: brain derived neurotrophic factor, neurotrophin-4

PDB Compounds: (B:) protein (neurotrophin-4)

SCOP Domain Sequences for d1b8mb_:

Sequence, based on SEQRES records:

>d1b8mb_ g.17.1.3 (B:) Neurotrophin 4, NT4 {Human (Homo sapiens) [TaxId: 9606]}
gelavcdavsgwvtdrrtavdlrgrevevlgevpaaggsplrqyffetrckadnaeeggp
gaggggcrgvdrrhwvseckakqsyvraltadaqgrvgwrwiridtacvctllsrtgra

Sequence, based on observed residues (ATOM records):

>d1b8mb_ g.17.1.3 (B:) Neurotrophin 4, NT4 {Human (Homo sapiens) [TaxId: 9606]}
gelavcdavsgwvtdrrtavdlrgrevevlgevpaaggsplrqyffetrckaaggpgagg
ggcrgvdrrhwvseckakqsyvraltadaqgrvgwrwiridtacvctllsrtgra

Timeline for d1b8mb_:

• d1b8mb_ first appeared (with stable ids) in SCOP 1.55
  
• d1b8mb_ appears in SCOP 1.71
  
• d1b8mb_ appears in SCOP 1.75
  
• d1b8mb_ appears in the current release, SCOPe 2.08