SCOP 1.75: Domain d1b8ma_: 1b8m A:

Lineage for d1b8ma_ (1b8m A:)

1. Root: SCOP 1.75

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (7 families)

5. Family g.17.1.3: Neurotrophin [57520] (4 proteins)

6. Protein Brain-derived neurotrophic factor, BDNF [88882] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88883] (2 PDB entries)

8. Domain d1b8ma_: 1b8m A: [44797]
   Other proteins in same PDB: d1b8mb_
   heterodimer with NT4

Details for d1b8ma_

PDB Entry: 1b8m, 2.75 Å

PDB Description: brain derived neurotrophic factor, neurotrophin-4

PDB Compounds: (A:) protein (brain derived neurotrophic factor)

SCOP Domain Sequences for d1b8ma_:

Sequence; same for both SEQRES and ATOM records:

>d1b8ma_ g.17.1.3 (A:) Brain-derived neurotrophic factor, BDNF {Human (Homo sapiens) [TaxId: 9606]}
gelsvcdsisewvtaadkktavdmsggtvtvlekvpvskgqlkqyfyetkcnpmgytkeg
crgidkrhwnsqcrttqsyvraltmdskkrigwrfiridtscvctltik

Timeline for d1b8ma_:

• d1b8ma_ first appeared (with stable ids) in SCOP 1.55
  
• d1b8ma_ appears in SCOP 1.73
  
• d1b8ma_ appears in SCOPe 2.01
  
• d1b8ma_ appears in the current release, SCOPe 2.08