SCOP 1.71: Domain d4htci_: 4htc I:

Lineage for d4htci_ (4htc I:)

1. Root: SCOP 1.71

2. Class g: Small proteins [56992] (79 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.15: Leech antihemostatic proteins [57262] (2 families)

5. Family g.3.15.2: Hirudin-like [57270] (3 proteins)

6. Protein Hirudin [57271] (1 species)

7. Species Leech (Hirudo medicinalis) [TaxId:6421] [57272] (8 PDB entries)

8. Domain d4htci_: 4htc I: [44368]
   Other proteins in same PDB: d4htc.1
   complexed with nag

Details for d4htci_

PDB Entry: 4htc, 2.3 Å

PDB Description: the refined structure of the hirudin-thrombin complex

SCOP Domain Sequences for d4htci_:

Sequence, based on SEQRES records:

>d4htci_ g.3.15.2 (I:) Hirudin {Leech (Hirudo medicinalis)}
itytdctesgqnlclcegsnvcgkgnkcilgsngkgnqcvtgegtpkpeshnngdfeeip
eeylq

Sequence, based on observed residues (ATOM records):

>d4htci_ g.3.15.2 (I:) Hirudin {Leech (Hirudo medicinalis)}
itytdctesgqnlclcegsnvcgkgnkcilggnqcvtgegtpkpeshnngdfeeipeeyl
q

Timeline for d4htci_:

• d4htci_ first appeared (with stable ids) in SCOP 1.55
  
• d4htci_ appears in SCOP 1.69
  
• d4htci_ appears in SCOP 1.73
  
• d4htci_ appears in the current release, SCOPe 2.08