SCOPe 2.03: Domain d1af3a_: 1af3 A:

Lineage for d1af3a_ (1af3 A:)

1. Root: SCOPe 2.03

2. Class f: Membrane and cell surface proteins and peptides [56835] (57 folds)

3. Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
   multi-helical domains of various folds which is thought to unfold in the membrane

4. Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families)
   PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain

5. Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
   Pfam PF00452

6. Protein Apoptosis regulator Bcl-xL [56856] (3 species)

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [56858] (1 PDB entry)

8. Domain d1af3a_: 1af3 A: [43397]

Details for d1af3a_

PDB Entry: 1af3, 2.5 Å

PDB Description: rat bcl-xl an apoptosis inhibitory protein

PDB Compounds: (A:) apoptosis regulator bcl-x

SCOPe Domain Sequences for d1af3a_:

Sequence, based on SEQRES records:

>d1af3a_ f.1.4.1 (A:) Apoptosis regulator Bcl-xL {Norway rat (Rattus norvegicus) [TaxId: 10116]}
sqsnrelvvdflsyklsqkgyswsqfsdveenrteapeeteperetpsaingnpswhlad
spavngatghsssldarevipmaavkqalreagdefelryrrafsdltsqlhitpgtayq
sfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaswmatylndhlepw
iqenggwdtfvdlyg

Sequence, based on observed residues (ATOM records):

>d1af3a_ f.1.4.1 (A:) Apoptosis regulator Bcl-xL {Norway rat (Rattus norvegicus) [TaxId: 10116]}
sqsnrelvvdflsyklsqkgyswsqfsdvipmaavkqalreagdefelryrrafsdltsq
lhitpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaswma
tylndhlepwiqenggwdtfvdlyg

Timeline for d1af3a_:

• d1af3a_ first appeared (with stable ids) in SCOP 1.55, called d1af3__
  
• d1af3a_ appears in SCOPe 2.02
  
• d1af3a_ appears in SCOPe 2.04
  
• d1af3a_ appears in the current release, SCOPe 2.08