SCOP 1.67: Domain d1ej9a2: 1ej9 A:203-430

Lineage for d1ej9a2 (1ej9 A:203-430)

1. Root: SCOP 1.67

2. Class e: Multi-domain proteins (alpha and beta) [56572] (40 folds)

3. Fold e.15: Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56740] (1 superfamily)
   2 domains: alpha+beta and all-beta

4. Superfamily e.15.1: Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56741] (1 family)

5. Family e.15.1.1: Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56742] (1 protein)

6. Protein Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56743] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56744] (9 PDB entries)

8. Domain d1ej9a2: 1ej9 A:203-430 [43265]
   Other proteins in same PDB: d1ej9a1
   protein/DNA complex; mutant

Details for d1ej9a2

PDB Entry: 1ej9, 2.6 Å

PDB Description: crystal structure of human topoisomerase i dna complex

SCOP Domain Sequences for d1ej9a2:

Sequence; same for both SEQRES and ATOM records:

>d1ej9a2 e.15.1.1 (A:203-430) Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment {Human (Homo sapiens)}
wkwweeerypegikwkflehkgpvfappyeplpenvkfyydgkvmklspkaeevatffak
mldheyttkeifrknffkdwrkemtneekniitnlskcdftqmsqyfkaqtearkqmske
eklkikeenekllkeygfcimdnhkerianfkieppglfrgrgnhpkmgmlkrrimpedi
iincskdakvpspppghkwkevrhdnkvtwlvswteniqgsikyimln

Timeline for d1ej9a2:

• d1ej9a2 first appeared (with stable ids) in SCOP 1.55
  
• d1ej9a2 appears in SCOP 1.65
  
• d1ej9a2 appears in SCOP 1.69
  
• d1ej9a2 appears in the current release, SCOPe 2.08