Lineage for d1cy6a_ (1cy6 A:)

  1. Root: SCOP 1.63
  2. 266016Class e: Multi-domain proteins (alpha and beta) [56572] (39 folds)
  3. 266966Fold e.10: Prokaryotic type I DNA topoisomerase [56711] (1 superfamily)
    4 domains: (1) Toprim alpha/beta; (2&4) "winged helix"-like; (3) barrel: n=6, S=8
  4. 266967Superfamily e.10.1: Prokaryotic type I DNA topoisomerase [56712] (1 family) (S)
    duplication: the protein chain passing through the domains 2-4 makes two structural repeats
    The active site is formed by the toprim and "winged helix" domains (domains 1 and 4); these two domains are also found in the type II topoisomerase (DNA gyrase A) and in the alpha subunit of topoisomerase IV
  5. 266968Family e.10.1.1: Prokaryotic type I DNA topoisomerase [56713] (3 proteins)
    domain 4 contains the catalytic tyrosine residue
  6. 266969Protein DNA topoisomerase I, 67K N-terminal domain [56714] (1 species)
  7. 266970Species Escherichia coli [TaxId:562] [56715] (10 PDB entries)
  8. 266982Domain d1cy6a_: 1cy6 A: [43247]
    complexed with po4, t3p

Details for d1cy6a_

PDB Entry: 1cy6 (more details), 2.5 Å

PDB Description: complex of e.coli dna topoisomerase i with 3' thymidine monophosphate

SCOP Domain Sequences for d1cy6a_:

Sequence, based on SEQRES records: (download)

>d1cy6a_ e.10.1.1 (A:) DNA topoisomerase I, 67K N-terminal domain {Escherichia coli}
gkalvivespakaktinkylgsdyvvkssvghirdlptsgsaakksadststktakkpkk
dergalvnrmgvdpwhnweahyevlpgkekvvselkqlaekadhiylatdldregeaiaw
hlreviggddarysrvvfneitknairqafnkpgelnidrvnaqqarrfmdrvvgymvsp
llwkkiarglsagrvqsvavrlvverereikafvpeefwevdastttpsgealalqvthq
ndkpfrpvnkeqtqaavsllekarysvleredkpttskpgapfitstlqqaastrlgfgv
kktmmmaqrlyeagyitymrtdstnlsqdavnmvrgyisdnfgkkylpespnqyaskens
qeaheairpsdvnvmaeslkdmeadaqklyqliwrqfvacqmtpakydsttltvgagdfr
lkargrilrfdgwtkvmpalrkgdedrilpavnkgdaltlveltpaqhftkpparfseas
lvkelekrgigrpstyasiistiqdrgyvrvenrrfyaekmgeivtdrleenfrelmnyd
ftaqmensldqvanheaewkavldhffsdftqqldkaekdpeeggmrpnqmvlt

Sequence, based on observed residues (ATOM records): (download)

>d1cy6a_ e.10.1.1 (A:) DNA topoisomerase I, 67K N-terminal domain {Escherichia coli}
gkalvivespakaktinkylgsdyvvkssvghirdlptdergalvnrmgvdpwhnweahy
evlpgkekvvselkqlaekadhiylatdldregeaiawhlreviggddarysrvvfneit
knairqafnkpgelnidrvnaqqarrfmdrvvgymvspllwkkiarglsagrvqsvavrl
vverereikafvpeefwevdastttpsgealalqvthqndkpfrpvnkeqtqaavsllek
arysvleredkpttskpgapfitstlqqaastrlgfgvkktmmmaqrlyeagyitymrtd
stnlsqdavnmvrgyisdnfgkkylpespnqyaaheairpsdvnvmaeslkdmeadaqkl
yqliwrqfvacqmtpakydsttltvgagdfrlkargrilrfdgwtkvmpalredrilpav
nkgdaltlveltpaqhftkpparfseaslvkelekrgigrpstyasiistiqdrgyvrve
nrrfyaekmgeivtdrleenfrelmnydftaqmensldqvanheaewkavldhffsdftq
qldkaekdpeeggmrpnqmvlt

SCOP Domain Coordinates for d1cy6a_:

Click to download the PDB-style file with coordinates for d1cy6a_.
(The format of our PDB-style files is described here.)

Timeline for d1cy6a_: