SCOPe 2.07: Domain d1c2pa1: 1c2p A:3-563

Lineage for d1c2pa1 (1c2p A:3-563)

1. Root: SCOPe 2.07

2. Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (8 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein Viral RNA polymerase [56695] (17 species)

7. Species Hepatitis C virus [TaxId:11103] [56697] (72 PDB entries)

8. Domain d1c2pa1: 1c2p A:3-563 [43117]
   Other proteins in same PDB: d1c2pa2, d1c2pb2

Details for d1c2pa1

PDB Entry: 1c2p, 1.9 Å

PDB Description: hepatitis c virus ns5b rna-dependent rna polymerase

PDB Compounds: (A:) RNA-dependent RNA polymerase

SCOPe Domain Sequences for d1c2pa1:

Sequence, based on SEQRES records:

>d1c2pa1 e.8.1.4 (A:3-563) Viral RNA polymerase {Hepatitis C virus [TaxId: 11103]}
sytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvldd
hyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhihsv
wkdlledtvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvstl
pqvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiyqc
cdlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkasaa
craaklqdctmlvngddlvvicesagvqedaaslrafteamtrysappgdppqpeydlel
itscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwar
milmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspgei
nrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpipaa
sqldlsgwfvagysggdiyhs

Sequence, based on observed residues (ATOM records):

>d1c2pa1 e.8.1.4 (A:3-563) Viral RNA polymerase {Hepatitis C virus [TaxId: 11103]}
sytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvldd
hyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhihsv
wkdlledtvtpidttimaknevfcvqrkparlivfpdlgvrvcekmalydvvstlpqvvm
gssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiyqccdlap
earqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkasaacraak
lqdctmlvngddlvvicesagvqedaaslrafteamtrysappgdppqpeydlelitscs
snvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwarmilmt
hffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspgeinrvas
clrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpipaasqldl
sgwfvagysggdiyhs

Timeline for d1c2pa1:

• d1c2pa1 first appeared (with stable ids) in SCOP 1.55, called d1c2pa_
  
• d1c2pa1 appears in SCOPe 2.06
  
• d1c2pa1 appears in the current release, SCOPe 2.08