SCOP 1.73: Domain d1c0tb_: 1c0t B:

Lineage for d1c0tb_ (1c0t B:)

1. Root: SCOP 1.73

2. Class e: Multi-domain proteins (alpha and beta) [56572] (53 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (2 proteins)

6. Protein HIV-1 reverse transcriptase [56689] (2 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (90 PDB entries)

8. Domain d1c0tb_: 1c0t B: [43083]
   Other proteins in same PDB: d1c0ta1
   complexed with bm1

Details for d1c0tb_

PDB Entry: 1c0t, 2.7 Å

PDB Description: crystal structure of hiv-1 reverse transcriptase in complex with bm+21.1326

PDB Compounds: (B:) hiv-1 reverse transcriptase (b-chain)

SCOP Domain Sequences for d1c0tb_:

Sequence, based on SEQRES records:

>d1c0tb_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
kdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfr
kytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymd
dlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpiv
lpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelae
nreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndv
kqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvkl
wyq

Sequence, based on observed residues (ATOM records):

>d1c0tb_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
kdstkwrklvdfrelnkrtqdfhpaglkkkksvtvldvgdayfsvpldedfrkytaftip
sinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgelh
pdkwtvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkaltevipl
teeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkya
rmrgahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewe
fvntpplvklwyq

Timeline for d1c0tb_:

• d1c0tb_ first appeared (with stable ids) in SCOP 1.55, called d1c0tb1
  
• d1c0tb_ appears in SCOP 1.71
  
• d1c0tb_ appears in SCOP 1.75
  
• d1c0tb_ appears in the current release, SCOPe 2.08