SCOP 1.67: Domain d1rtjb1: 1rtj B:2-431

Lineage for d1rtjb1 (1rtj B:2-431)

1. Root: SCOP 1.67

2. Class e: Multi-domain proteins (alpha and beta) [56572] (40 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (2 proteins)

6. Protein HIV-1 reverse transcriptase [56689] (2 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (71 PDB entries)

8. Domain d1rtjb1: 1rtj B:2-431 [43035]
   Other proteins in same PDB: d1rtja1
   complexed with cya

Details for d1rtjb1

PDB Entry: 1rtj, 2.35 Å

PDB Description: mechanism of inhibition of hiv-1 reverse transcriptase by non-nucleoside inhibitors

SCOP Domain Sequences for d1rtjb1:

Sequence, based on SEQRES records:

>d1rtjb1 e.8.1.2 (B:2-431) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1}
ispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvf
aikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpld
edfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviy
qymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtv
qpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeael
elaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgah
tndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpp
lvklwyqlek

Sequence, based on observed residues (ATOM records):

>d1rtjb1 e.8.1.2 (B:2-431) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1}
ispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvf
aikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpld
edfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviy
qymddlyvgsdleigqhrtkieelrqhllrwglttpgyelhpdkwtvqpivlpekdswtv
ndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepv
hgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqk
ittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklwyqlek

Timeline for d1rtjb1:

• d1rtjb1 first appeared (with stable ids) in SCOP 1.55
  
• d1rtjb1 appears in SCOP 1.65
  
• d1rtjb1 appears in SCOP 1.69
  
• d1rtjb1 appears in the current release, SCOPe 2.08