SCOPe 2.04: Domain d4bdpa2: 4bdp A:469-876

Lineage for d4bdpa2 (4bdp A:469-876)

1. Root: SCOPe 2.04

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.1: DNA polymerase I [56673] (5 proteins)

6. Protein DNA polymerase I (Klenow fragment) [56674] (3 species)

7. Species Bacillus stearothermophilus, newly identified strain as yet unnamed [TaxId:1422] [56677] (44 PDB entries)
   Uniprot Q5KWC1 299-878 # 99% sequence identity; Geobacillus kaustophilus TaxID:1462
   Uniprot Q45458 298-876 # 88% sequence identity

8. Domain d4bdpa2: 4bdp A:469-876 [43003]
   Other proteins in same PDB: d4bdpa1
   protein/DNA complex; complexed with mg, so4

Details for d4bdpa2

PDB Entry: 4bdp, 1.8 Å

PDB Description: crystal structure of bacillus dna polymerase i fragment complexed to 11 base pairs of duplex dna after addition of two datp residues

PDB Compounds: (A:) protein (DNA polymerase I)

SCOPe Domain Sequences for d4bdpa2:

Sequence; same for both SEQRES and ATOM records:

>d4bdpa2 e.8.1.1 (A:469-876) DNA polymerase I (Klenow fragment) {Bacillus stearothermophilus, newly identified strain as yet unnamed [TaxId: 1422]}
eqdrllveleqplssilaemefagvkvdtkrleqmgkelaeqlgtveqriyelagqefni
nspkqlgvilfeklqlpvlkktktgystsadvleklapyheivenilhyrqlgklqstyi
egllkvvrpdtkkvhtifnqaltqtgrlsstepnlqnipirleegrkirqafvpsesdwl
ifaadysqielrvlahiaeddnlmeafrrdldihtktamdifqvsedevtpnmrrqakav
nfgivygisdyglaqnlnisrkeaaefieryfesfpgvkrymenivqeakqkgyvttllh
rrrylpditsrnfnvrsfaermamntpiqgsaadiikkamidlnarlkeerlqahlllqv
hdelileapkeemerlcrlvpevmeqavtlrvplkvdyhygstwydak

Timeline for d4bdpa2:

• d4bdpa2 first appeared (with stable ids) in SCOP 1.55
  
• d4bdpa2 appears in SCOPe 2.03
  
• d4bdpa2 appears in SCOPe 2.05
  
• d4bdpa2 appears in the current release, SCOPe 2.08