SCOPe 2.08: Domain d1kfda2: 1kfd A:519-928

Lineage for d1kfda2 (1kfd A:519-928)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (9 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.1: DNA polymerase I [56673] (5 proteins)
   in the multi-domain class (e), this applies to domains with different numbers of (sub)domains than the most common domain
   

6. Protein DNA polymerase I (Klenow fragment) [56674] (3 species)

7. Species Escherichia coli [TaxId:562] [56675] (14 PDB entries)

8. Domain d1kfda2: 1kfd A:519-928 [42987]
   Other proteins in same PDB: d1kfda1
   protein/DNA complex; complexed with ctp

Details for d1kfda2

PDB Entry: 1kfd, 3.9 Å

PDB Description: crystal structures of the klenow fragment of dna polymerase i complexed with deoxynucleoside triphosphate and pyrophosphate

PDB Compounds: (A:) DNA polymerase I klenow fragment

SCOPe Domain Sequences for d1kfda2:

Sequence, based on SEQRES records:

>d1kfda2 e.8.1.1 (A:519-928) DNA polymerase I (Klenow fragment) {Escherichia coli [TaxId: 562]}
hkgplnvfeniemplvpvlsrierngvkidpkvlhnhseeltlrlaelekkaheiageef
nlsstkqlqtilfekqgikplkktpggapstseevleelaldyplpkvileyrglaklks
tytdklplminpktgrvhtsyhqavtatgrlsstdpnlqnipvrneegrrirqafiaped
yvivsadysqielrimahlsrdkglltafaegkdihrataaevfglpletvtseqrrsak
ainfgliygmsafglarqlniprkeaqkymdlyferypgvleymertraqakeqgyvetl
dgrrlylpdikssngarraaaeraainapmqgtaadiikramiavdawlqaeqprvrmim
qvhdelvfevhkddvdavakqihqlmenctrldvpllvevgsgenwdqah

Sequence, based on observed residues (ATOM records):

>d1kfda2 e.8.1.1 (A:519-928) DNA polymerase I (Klenow fragment) {Escherichia coli [TaxId: 562]}
hkgplnvfeniemplvpvlsrierngvkidpkvlhnhseeltlrlaelekkaheiadypl
pkvileyrglaklkstytdklplminpktgrvhtsyhqavtatgrlsstdpnlqnipvrn
eegrrirqafiapedyvivsadysqielrimahlsrdkglltafaegkdihrataaevfg
lpletvtseqrrsakainfgliygmsafglarqlniprkeaqkymdlyferypgvleyme
rtraqakeqgyvetldgrrlylpdikssngarraaaeraainapmqgtaadiikramiav
dawlqaeqprvrmimqvhdelvfevhkddvdavakqihqlmenctrldvpllvevgsgen
wdqah

Timeline for d1kfda2:

• d1kfda2 first appeared (with stable ids) in SCOP 1.55, called d1kfd_2
  
• d1kfda2 appears in SCOPe 2.07