SCOP 1.73: Domain d1egeb2: 1ege B:10-241

Lineage for d1egeb2 (1ege B:10-241)

1. Root: SCOP 1.73

2. Class e: Multi-domain proteins (alpha and beta) [56572] (53 folds)

3. Fold e.6: Acyl-CoA dehydrogenase NM domain-like [56644] (1 superfamily)
   2 domains: (1) all-alpha: 5 helices; (2) contains an open beta-sheet barrel: n*=5, S*=8; complex topology

4. Superfamily e.6.1: Acyl-CoA dehydrogenase NM domain-like [56645] (2 families)
   flavoprotein: binds FAD; constituent families differ in the numbers of C-terminal domains (four-helical bundles)

5. Family e.6.1.1: Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains [56646] (9 proteins)

6. Protein Medium chain acyl-CoA dehydrogenase, NM domains [56649] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56651] (5 PDB entries)

8. Domain d1egeb2: 1ege B:10-241 [42866]
   Other proteins in same PDB: d1egea1, d1egeb1, d1egec1, d1eged1

Details for d1egeb2

PDB Entry: 1ege, 2.75 Å

PDB Description: structure of t255e, e376g mutant of human medium chain acyl-coa dehydrogenase

PDB Compounds: (B:) medium chain acyl-coa dehydrogenase

SCOP Domain Sequences for d1egeb2:

Sequence; same for both SEQRES and ATOM records:

>d1egeb2 e.6.1.1 (B:10-241) Medium chain acyl-CoA dehydrogenase, NM domains {Human (Homo sapiens) [TaxId: 9606]}
lgfsfefteqqkefqatarkfareeiipvaaeydktgeypvplirrawelglmnthipen
cgglglgtfdacliseelaygctgvqtaiegnslgqmpiiiagndqqkkkylgrmteepl
mcaycvtepgagsdvagiktkaekkgdeyiingqkmwitnggkanwyfllarsdpdpkap
ankaftgfiveadtpgiqigrkelnmgqrcsdtrgivfedvkvpkenvligd

Timeline for d1egeb2:

• d1egeb2 first appeared (with stable ids) in SCOP 1.55
  
• d1egeb2 appears in SCOP 1.71
  
• d1egeb2 appears in SCOP 1.75
  
• d1egeb2 appears in the current release, SCOPe 2.08