SCOPe 2.07: Domain d2antl_: 2ant L:

Lineage for d2antl_ (2ant L:)

1. Root: SCOPe 2.07

2. Class e: Multi-domain proteins (alpha and beta) [56572] (71 folds)

3. Fold e.1: Serpins [56573] (1 superfamily)
   contains a cluster of helices and a beta-sandwich

4. Superfamily e.1.1: Serpins [56574] (2 families)

5. Family e.1.1.1: Serpins [56575] (17 proteins)
   automatically mapped to Pfam PF00079

6. Protein Antithrombin [56584] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56586] (27 PDB entries)
   Uniprot P01008

8. Domain d2antl_: 2ant L: [42651]
   complexed with naa

Details for d2antl_

PDB Entry: 2ant, 2.6 Å

PDB Description: the 2.6 a structure of antithrombin indicates a conformational change at the heparin binding site

PDB Compounds: (L:) antithrombin

SCOPe Domain Sequences for d2antl_:

Sequence, based on SEQRES records:

>d2antl_ e.1.1.1 (L:) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
ictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfattfyqhl
adskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffakl
ncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraai
nkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadges
csasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqe
wldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsd
afhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplntiifmgrv
anpcvk

Sequence, based on observed residues (ATOM records):

>d2antl_ e.1.1.1 (L:) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
ictakdipmnpmciyrsatnrrvwelskansrfattfyqhladskndndniflsplsist
afamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrkankssklvsanr
lfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnktegritdvipse
aineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqegkfryrrvae
gtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemmlvvhmprfri
edgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkaflevneegseaaas
tavviagrslnrpflvfirevplntiifmgrvanpcvk

Timeline for d2antl_:

• d2antl_ first appeared (with stable ids) in SCOP 1.55
  
• d2antl_ appears in SCOPe 2.06
  
• d2antl_ appears in the current release, SCOPe 2.08