SCOP 1.75: Domain d2anti_: 2ant I:

Lineage for d2anti_ (2ant I:)

1. Root: SCOP 1.75

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.1: Serpins [56573] (1 superfamily)
   contains a cluster of helices and a beta-sandwich

4. Superfamily e.1.1: Serpins [56574] (1 family)

5. Family e.1.1.1: Serpins [56575] (16 proteins)

6. Protein Antithrombin [56584] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56586] (25 PDB entries)
   Uniprot P01008

8. Domain d2anti_: 2ant I: [42650]

Details for d2anti_

PDB Entry: 2ant, 2.6 Å

PDB Description: the 2.6 a structure of antithrombin indicates a conformational change at the heparin binding site

PDB Compounds: (I:) antithrombin

SCOP Domain Sequences for d2anti_:

Sequence, based on SEQRES records:

>d2anti_ e.1.1.1 (I:) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
fffaklncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
pevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
dlyvsdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplnti
ifmgrvanpcvk

Sequence, based on observed residues (ATOM records):

>d2anti_ e.1.1.1 (I:) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
hgspvdictakprdipmnpmciyrspekkatnrrvwelskansrfattfyqhladskndn
dniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrk
ankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnk
tegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmy
qegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldelee
mmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkafl
evneegseaaastavviagrslnpnrvtfkanrpflvfirevplntiifmgrvanpcvk

Timeline for d2anti_:

• d2anti_ first appeared (with stable ids) in SCOP 1.55
  
• d2anti_ appears in SCOP 1.73
  
• d2anti_ appears in SCOPe 2.01
  
• d2anti_ appears in the current release, SCOPe 2.08