SCOPe 2.08: Domain d1atha_: 1ath A:

Lineage for d1atha_ (1ath A:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.1: Serpins [56573] (1 superfamily)
   contains a cluster of helices and a beta-sandwich

4. Superfamily e.1.1: Serpins [56574] (2 families)

5. Family e.1.1.1: Serpins [56575] (17 proteins)
   automatically mapped to Pfam PF00079

6. Protein Antithrombin [56584] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56586] (27 PDB entries)
   Uniprot P01008

8. Domain d1atha_: 1ath A: [42646]

Details for d1atha_

PDB Entry: 1ath, 3.2 Å

PDB Description: the intact and cleaved human antithrombin iii complex as a model for serpin-proteinase interactions

PDB Compounds: (A:) antithrombin III

SCOPe Domain Sequences for d1atha_:

Sequence, based on SEQRES records:

>d1atha_ e.1.1.1 (A:) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
ictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfattfyqhl
adskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffakl
ncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraai
nkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadges
csasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqe
wldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsd
afhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplntiifmgrv
anpcv

Sequence, based on observed residues (ATOM records):

>d1atha_ e.1.1.1 (A:) Antithrombin {Human (Homo sapiens) [TaxId: 9606]}
ictciyrrrvwelskansrfattfyqhladskndndniflsplsistafamtklgacndt
lqqlmevfkfdtisektsdqihfffaklncrlyrssklvsanrlfgdksltfnetyqdis
elvygaklqpldfkenaeqsraainkwvsnktegritdvipseaineltvlvlvntiyfk
glwkskfspentrkelfykadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmv
lilpkpekslakvekeltpevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvd
lfspeksklpgivaegrddlyvsdafhkaflevneegseaaastavviagrslnpnrvtf
kanrpflvfirevplntiifmgrvanpcv

Timeline for d1atha_:

• d1atha_ first appeared (with stable ids) in SCOP 1.55
  
• d1atha_ appears in SCOPe 2.07