SCOPe 2.08: Domain d1dqaa4: 1dqa A:462-586,A:704-870

Lineage for d1dqaa4 (1dqa A:462-586,A:704-870)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.179: Substrate-binding domain of HMG-CoA reductase [56541] (1 superfamily)
   unusual fold

4. Superfamily d.179.1: Substrate-binding domain of HMG-CoA reductase [56542] (1 family)

5. Family d.179.1.1: Substrate-binding domain of HMG-CoA reductase [56543] (1 protein)

6. Protein Substrate-binding domain of HMG-CoA reductase [56544] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56545] (9 PDB entries)

8. Domain d1dqaa4: 1dqa A:462-586,A:704-870 [42585]
   Other proteins in same PDB: d1dqaa1, d1dqab1, d1dqac1, d1dqad1
   complexed with coa, mah, nap

Details for d1dqaa4

PDB Entry: 1dqa, 2 Å

PDB Description: complex of the catalytic portion of human hmg-coa reductase with hmg, coa, and nadp+

PDB Compounds: (A:) protein (hmg-coa reductase)

SCOPe Domain Sequences for d1dqaa4:

Sequence; same for both SEQRES and ATOM records:

>d1dqaa4 d.179.1.1 (A:462-586,A:704-870) Substrate-binding domain of HMG-CoA reductase {Human (Homo sapiens) [TaxId: 9606]}
lsdaeiiqlvnakhipaykletliethergvsirrqllskklsepsslqylpyrdynysl
vmgaccenvigympipvgvagplcldekefqvpmattegclvastnrgcraiglgggass
rvladXksvvceavipakvvrevlkttteamievninknlvgsamagsiggynahaaniv
taiyiacgqdaaqnvgssncitlmeasgptnedlyisctmpsieigtvgggtnllpqqac
lqmlgvqgackdnpgenarqlarivcgtvmagelslmaalaaghlvkshmihn

Timeline for d1dqaa4:

• d1dqaa4 first appeared (with stable ids) in SCOP 1.55
  
• d1dqaa4 appears in SCOPe 2.07