Lineage for d5scta1 (5sct A:1-159)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2903429Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2903430Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2903431Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. 2903517Protein Dihydrofolate reductase, prokaryotic type [53599] (9 species)
  7. 2903663Species Mycobacterium tuberculosis [TaxId:1773] [53602] (24 PDB entries)
  8. 3086104Domain d5scta1: 5sct A:1-159 [422421]
    Other proteins in same PDB: d5scta2
    automated match to d6ddwa_
    complexed with h03, nap

Details for d5scta1

PDB Entry: 5sct (more details), 1.55 Å

PDB Description: crystal structure of dihydrofolate reductase from mycobacterium tuberculosis bound to nadp and sddc inhibitor sddc-783
PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d5scta1:

Sequence; same for both SEQRES and ATOM records: (download)

>d5scta1 c.71.1.1 (A:1-159) Dihydrofolate reductase, prokaryotic type {Mycobacterium tuberculosis [TaxId: 1773]}

SCOPe Domain Coordinates for d5scta1:

Click to download the PDB-style file with coordinates for d5scta1.
(The format of our PDB-style files is described here.)

Timeline for d5scta1:

  • d5scta1 is new in SCOPe 2.08-stable

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