SCOPe 2.08: Domain d7e0aa_: 7e0a A:

Lineage for d7e0aa_ (7e0a A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (172 PDB entries)
   Uniprot P37231 232-505

8. Domain d7e0aa_: 7e0a A: [421429]
   automated match to d1nyxa_
   complexed with ewr

Details for d7e0aa_

PDB Entry: 7e0a, 1.77 Å

PDB Description: x-ray structure of human ppargamma ligand binding domain-saroglitazar co-crystals obtained by co-crystallization

PDB Compounds: (A:) Isoform 2 of Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d7e0aa_:

Sequence, based on SEQRES records:

>d7e0aa_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
dqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedk
ikfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkyg
vheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleldd
sdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtd
lrqivtehvqllqvikktetdmslhpllqeiykdl

Sequence, based on observed residues (ATOM records):

>d7e0aa_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
dqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedk
ikfkhkevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytm
laslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifia
viilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivteh
vqllqvikktetdmslhpllqeiykdl

Timeline for d7e0aa_:

• d7e0aa_ is new in SCOPe 2.08-stable