SCOPe 2.08: Domain d1ceta2: 1cet A:164-329

Lineage for d1ceta2 (1cet A:164-329)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
   unusual fold, defines family

4. Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families)

5. Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
   N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
   automatically mapped to Pfam PF02866

6. Protein Lactate dehydrogenase [56339] (20 species)

7. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [56343] (14 PDB entries)

8. Domain d1ceta2: 1cet A:164-329 [42131]
   Other proteins in same PDB: d1ceta1
   complexed with clq

Details for d1ceta2

PDB Entry: 1cet, 2.05 Å

PDB Description: chloroquine binds in the cofactor binding site of plasmodium falciparum lactate dehydrogenase.

PDB Compounds: (A:) protein (l-lactate dehydrogenase)

SCOPe Domain Sequences for d1ceta2:

Sequence; same for both SEQRES and ATOM records:

>d1ceta2 d.162.1.1 (A:164-329) Lactate dehydrogenase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
ggvldtsrlkyyisqklnvcprdvnahivgahgnkmvllkryitvggiplqefinnklis
daeleaifdrtvntaleivnlhaspyvapaaaiiemaesylkdlkkvlicstllegqygh
sdifggtpvvlgangveqvielqlnseekakfdeaiaetkrmkala

Timeline for d1ceta2:

• d1ceta2 first appeared (with stable ids) in SCOP 1.55
  
• d1ceta2 appears in SCOPe 2.07