SCOPe 2.05: Domain d2hlpa2: 2hlp A:163-330

Lineage for d2hlpa2 (2hlp A:163-330)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
   unusual fold, defines family

4. Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families)

5. Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
   N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
   automatically mapped to Pfam PF02866

6. Protein Malate dehydrogenase [56329] (12 species)

7. Species Haloarcula marismortui [TaxId:2238] [56335] (5 PDB entries)

8. Domain d2hlpa2: 2hlp A:163-330 [42108]
   Other proteins in same PDB: d2hlpa1, d2hlpb1
   complexed with cl, na; mutant

Details for d2hlpa2

PDB Entry: 2hlp, 2.59 Å

PDB Description: crystal structure of the e267r mutant of a halophilic malate dehydrogenase in the apo form

PDB Compounds: (A:) malate dehydrogenase

SCOPe Domain Sequences for d2hlpa2:

Sequence; same for both SEQRES and ATOM records:

>d2hlpa2 d.162.1.1 (A:163-330) Malate dehydrogenase {Haloarcula marismortui [TaxId: 2238]}
fggrldsarfryvlseefdapvqnvegtilgehgdaqvpvfskvrvdgtdpefsgdekeq
llgdlqesamdvierkgatewgpargvahmveailhdtgrvlpasvklegefghedtafg
vpvrlgsngveeivewdlddyeqdlmadaaeklsdqydkis

Timeline for d2hlpa2:

• d2hlpa2 first appeared (with stable ids) in SCOP 1.55
  
• d2hlpa2 appears in SCOPe 2.04
  
• d2hlpa2 appears in SCOPe 2.06
  
• d2hlpa2 appears in the current release, SCOPe 2.08